Catalogo dei Corsi di studio

SUSANNA SCARPA
Department Experimental Medicine
Viale Regina Elena 324- 00161 Rome- Italy
Work: 06-49973017
susanna.scarpa@uniroma1.it

Full Professor MED04
2001-now Full Professor of General Pathology, Dept Experimental Medicine, Faculty of Medicine and Dentistry, University Sapienza, Rome, Italy
1998-2001 Assistant Professor of General Pathology, Faculty of Medicine A Gemelli , Catholic University, Rome, Italy
1990-1998 Researcher, Dept Experimental Medicine, Faculty of Medicine, University Sapienza, Rome, Italy
1990 Specialist in Clinical Pathology, University Sapienza, Rome, Italy
1985-1990 Clinical Pathology Specialization, Faculty of Medicine, University Sapienza, Rome, Italy
1982-1985 Visiting Fellow, National Cancer Institute, National Institutes of Health, Bethesda, USA
1981 PhD in Biological Science, University of Padova, Italy

Didattica nei seguenti corsi:
1) Corso di Patologia e Fisiopatologia Generale I nel Corso Laurea Magistrale in Medicina e Chirurgia D
2) Corso di Patologia e Fisiopatologia Generale II nel Corso Laurea Magistrale in Medicina e Chirurgia D
3) Dottorato di Ricerca Medicina Molecolare Sapienza
4) Scuola Specializzazione "Farmacia Ospedaliera" Sapienza

Scientific Publications
Modesti A, Kalebic T, Scarpa S, Togo S, Liotta L, Triche TJ. Type V collagen in human amnion is a 12 nm fibrillar component of the pericellular interstitium. European Journal of Cell Biology 35: 246-255, 1984.
Verna R, Galli C, Pascale E, Pozzi D, D'Amore L, Scarpa S, Frati L, Modesti A: Prostaglandin-induced storage and secretion of esteroproteases in the mouse submaxillary gland. Cytobios 46: 37-41, 1986.
Scarpa S, Modesti A, Triche TJ: Extracellular matrix synthesis by undifferentiated childhood neoplasia. American Journal of Pathology 129: 74-85, 1987.
Scarpa S, D'Orazi G, Modesti M, Modesti A: Ewing's sarcoma lines synthesize laminin and fibronectin. Virchows Archives A 410: 375-381, 1987.
Tsokos M, Scarpa S, Ross RA, Triche TJ: Differentation of human neuroblastoma recapitulates neural crest development: study of morphology, neurotrasmitter enzymes and extracellular matrix proteins. American Journal of Pathology 128: 484-496, 1987.
Santoni A, Scarpa S, Morrone S, Punturieri A, Gismondi A, D'Orazi G, Testi R, Piccoli M, Frati L, Modesti A: Laminin production by Natural Killer Cells. Protides of Biological Fluids 35: 217-220, 1987.
Scarpa S, D'Orazi G, Modesti A, Valia S, Zucco F, Stammati A: Expression and synthesis of fibronectin and laminin by an intestinal epithelial cell line. Tissue & Cell 20: 305-312, 1988.
Scarpa S, Morstyn G, Carney DN, Modesti A, Triche TJ: Small cell lung cancer pure and variant types can be distinguished by their extracellular matrix synthesis in vitro. The European Respiratory Journal 1: 639-644, 1988.
Santoni A, Punturieri A, Morrone S, Scarpa S, Gismondi A, D'Orazi G, Piccoli M, Frati L, Modesti A: Laminin expression by rat lymphoid cells. The Italian Journal of Biochemistry 37: 244A-246A, 1988.
Scarpa S, Dominici C, Grammatico P, Del Porto G, Raschella` G, Castello M, Forni G, Modesti A: Establishment and characterization of a human neuroblastoma cell line. International Journal of Cancer, 43: 645-652, 1989.
Santoni A, Gismondi A, Morrone S, Procopio A, Modesti A, Scarpa S, D'Orazi G, Piccoli M, Frati L: Rat natural Killer cells synthesize fibronectin: possible involvement in the cytotoxic function. The Journal of Immunology 143: 2415-2421, 1989.
Morrone S, Scarpa S, Punturieri A, Testi R, Gismondi A, Santoni G, Piccoli M, Frati L, Modesti A, Santoni A: Laminin synthesis by NK cells and modulation of its expression by TPA. Experimental Cell Research 182: 543-549, 1989.
Scarpa S, Reddy MP, Bressani N, Mims S, Massari F, Triche TJ: A novel 500,000 Da, linear, single chain extracellular protein synthesized by several childhood tumors. The Italian Journal of Biochemistry 38: 330-348, 1989.
Caretto P, Forni M, D'Orazi G, Scarpa S, Feraiorni P, Jemma C, Modesti A, Ferrarini M, Roncella S, Foa` R, Forni G: Xenotransplantation in immunosuppressed nude mice of human solid tumors and acute leukemias directly from patients or in vitro cell lines. Research in Clinic and Laboratory 19: 231-243, 1989.
Silvestroni L, Menditto A, Modesti A, Scarpa S: Zinc uptake in human seminal spermatozoa: characterization and effects on cell membranes. Archives of Andrology 23: 97-103, 1989.
Carbonari M, Gaetano C, Cerchi M, Scarpa S, Modesti A, Fiorilli M: Expression of the natural killer antigen Leu 19/NKH-1 by human neural tumor cell lines. Journal of Immunological Research 1: 163-167, 1989.
Raschella` G, Negroni A, Giubilei C, Romeo A, Mauro F, Scarpa S, Castello M, Dominici C: Human neuroblastoma as model for studing tumor heterogeneity at genomic and trascriptional level. Clinical Chemistry and Enzymology Communications 2: 253-259, 1990.
Grammatico P, Lo Re ML, Scarpa S, Modesti A, Del Porto G: Human malignant melanoma: significance of chromosomal aberrations. Cancer Genetics and Cytogenetics 48: 237-242, 1990.
Bosco MC, Giovarelli M, Forni M, Modesti A, Scarpa S, Masuelli L, Forni G: Low doses of IL-4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently nonimmunogenic tumors and induce a tumor specific immune memory. The Journal of Immunology 145: 3136-3143, 1990.
Negroni A, Scarpa S, Romeo A, Ferrari S, Modesti A, Raschella` G: Decrease of proliferation rate and induction of differentiation by an MYCN antisense oligomer in a human neuroblastoma cell line. Cell Growth and Differentiation 2: 511-518, 1991.
Grammatico P, Scarpa S, Steindl K, Picardo M, Modesti A, Nazzaro-Porro M, Del Porto G:Effect of azelaic acid on viability, ultrastructure and karyotype of melanoma cells in long term culture. The Cancer Journal 4: 39-43, 1991.
Negroni A, Scarpa S, Romeo A, Ferrari S, Modesti A, Raschella` G: Decrease of proliferation rate and induction of differentiation by an MYCN antisense oligomer in a human neuroblastoma cell line. Cell Growth and Differentiation 2: 511-518, 1991.
Grammatico P, Scarpa S, Steindl K, Picardo M, Modesti A, Nazzaro-Porro M, Del Porto G: Effect of azelaic acid on viability, ultrastructure and karyotype of melanoma cells in long term culture. The Cancer Journal 4: 39-43, 1991.
Grammatico P, Modesti A, Steindl K, Scarpa S, Heouaine A, Del Porto G: Lentigo maligna: cytogenetic, ultrastructural and phenotypic characterization of a primary cell culture. Cancer Genetics and Cytogenetics 60: 141- 146, 1992.
Screpanti I, Meco D, Scarpa S, Morrone S, Frati L, Gulino A, Modesti A: Neuromodulatory loop mediated by nerve growth factor and interleukin 6 in thymic stromal cell cultures. Proceedings National Academy Science USA 89: 3209-3212, 1992.
Scarpa S, D'Orazi G, Ragano-Caracciolo M, Cardelli P, Masuelli L, Modesti A: Modulation of laminin synthesis in human neuroblastoma cells during retinoic acid induced differentiation. Cancer Letters 64: 31-37, 1992.
Gnessi L, Emidi A, Farini D, Scarpa S, Modesti A, Ciampani T, Silvestroni L, Spera G: Rat Leydig cells bind platelet- derived growth factor through specific receptors and produce platelet-derived growth factor- like molecules. Endocrinology 130: 2219-2224, 1992.
Gambella GR, Bellotti S, Cutolo M, Modesti A, Scarpa S, Novelli A, Ravera GB: Changes in fibronectin production in rat liver during cirrhotic evolution due to treatment with CCl4 and steroid hormones: correlation with plasmatic fibronectin. Pathologica 84: 343-361, 1992.
Modesti A, Masuelli L, Modica A, D'Orazi G, Scarpa S, Bosco M, Forni G: Ultrastructural evidence of the mechanisms responsible for interleukin-4-activated rejection of a spontaneous murine adenocarcinoma. International Journal of Cancer 53: 988-993, 1993.
Grammatico P, Scarpa S, Picardo M, Steindl K, Nazzaro-Porro M, Del Porto G: Karyotype modification in human malignant melanoma cell cultures after treatment with azelaic acid. Mutation Research 300: 119-123, 1993.
Gnessi L, Emidi A, Scarpa S, Palleschi S, Ragano-Caracciolo M, Silvestroni L, Modesti A, Spera G: Platelet-derived growth factors effects on purified testicular peritubular myoid cells: binding, cytosolic Ca++ increase, mitogenic activity, and extracellular matrix production enhancement. Endocrinology 133: 1880-1890, 1993.
Manna A, Scarpa S, Reale MG, Oppido PA, Frati L: Human meningioma and neuron specific enolase expression. The International Journal of Biological Markers 9: 146-147, 1994.
Grammatico P, Balus L, Scarpa S, Varesco L, Di Rosa C, Grammatico B, Del Porto G: Granulomatous Slack Skin: cytogenetic and molecular analysis. Cancer Genetics and Cytogenetics 72: 96-100, 1994.
Scarpa S, Mincione G, Ragano-Caracciolo M, Modesti A, Colletta G: Transforming growth factor alpha modulates replication and differentiation markers on a human neuroblastoma cell line. International Journal of Oncology 5: 547- 552, 1994.
Meco D, Scarpa S, Napolitano M, Maroder M, Bellavia D, De Maria R, Ragano-Caracciolo M, Frati L, Modesti A, Gulino A, Screpanti I: Modulation of fibronectin and thymic stromal cell-dependent thymocyte maturation by retinoic acid. The Journal of Immunology 153: 73-83, 1994.
Gaetano C, Melchiori A, Albini A, Benelli R, Falcioni R, Modesti A, Modica A, Scarpa S, Sacchi A: Retinoic acid negatively regulates beta4-integrin expression and suppresses the malignant phenotype in a Lewis lung carcinoma cell line. Clinical Experimental Metastasis 12: 63-72, 1994.
Martinotti S, Toniato E, Colagrande A, Alesse E, Alleva C, Screpanti I, Morrone S, Scarpa S, Frati L, Hayday AC, Piovella F, Gulino A: Heavy-metal modulation of the human intercellular adhesion molecule ICAM-I gene expression. Biochimica et Biophysica Acta 1261: 107-114, 1995.
Screpanti I, Romani L, Musiani P, Modesti A, Fattori E, Lazzaro D, Sellitto C, Scarpa S, Bellavia D, Lattanzio G, Bistoni F, Frati L, Cortese R, Gulino A, Ciliberto G, Costantini F, Poli V: Lymphoproliferative disorder and imbalanced T-helper response in C/EBPbeta-deficent mice. The EMBO Journal 14: 1932-1941, 1995.
Screpanti I, Scarpa S, Meco D, Bellavia D, Stuppia L, Frati L, Modesti A, Gulino A: Epidermal growth factor promotes a neural phenotype in thymic epithelial cells and enhances neuropoietic cytokine expression. The Journal of Cell Biology 130: 183-192, 1995.
Modesti A, Gulino A: Human immunodeficency virus type-1 tat protein modulates fibronectin expression in thymic epithelial cells and impairs in vitro thymocyte development. Cellular Immunology 168: 49-58, 1996.
Maroder M, Scarpa S, Screpanti I, Stigliano A, Meco D, Vacca A, Stuppia L, Frati L, Modesti A, Gulino A: Human immunodeficency virus type-1 tat protein modulates fibronectin expression in thymic epithelial cells and impairs in vitro thymocyte development. Cellular Immunology 168: 49-58, 1996.
Gentile V, Modesti A, La Pera G, Vasaturo F, Modica A, Prigiotti G, Di Silverio F, Scarpa S: Ultrastructural and immunohistochemical characterization of the tunica albuginea in Peyronie's disease and veno- occlusive dysfunction. Journal of Andrology 17: 96-103, 1996.
Scarpa S, Coppa A, Ragano-Caracciolo M, Mincione G, Giuffrida A, Modesti A, Colletta G: Transforming growth factor beta regulates differentiation and proliferation of human neuroblastoma. Experimental Cell Research 229: 147-154, 1996.
Scarpa S, Negroni A, Amendola R, Signorelli P, Calabretta B, Modesti A, Raschella G: Phenotypic and morphological characterization of neuroblastoma cells costitutively expressing B-myb. Journal of Neuro-oncology 31: 107-114, 1997.
Scarpa S, Giuffrida A, Palumbo C, Vasaturo F, Signorelli P, Forni G, Modesti M, Ferrantini M, Belardelli F, Musiani P, Modesti A: Extracellular matrix remodelling in a murine mammary adenocarcinoma transfected with the interferon alpha1 gene. J Pathol 181: 116-123, 1997.
Coppa A, Mincione G, Lazzareschi D, Ranieri A, Turco A, Lucignano B, Scarpa S, Ragano-Caracciolo M, Colletta G: Restored expression of transforming growth factor beta type II receptor in k-ras-transformed thyroid cells, TGFb- resistant, reverts their malignant phenotype. J Cell Physiol 172: 200-208, 1997.
Vasaturo F, Modesti A, Scarpa S: Interferon gamma modifies fibronectin and laminin synthesis in human neuroblastoma cell lines. Int J Oncol 12: 895-898, 1998.
Scarpa S, Giuffrida A, Fazi M, Coletti A, Palumbo C, Pass HI, Procopio A, Modesti A: Migration of mesothelioma cells correlates with histotype-specific synthesis of extracellular matrix. Int J Mol Med 4: 67-71, 1999.
Vacca A, Di Marcotullio L, Giannini G, Farina M, Scarpa S, Stopacciaro A, Calce A, Maroder M, Frati L, Screpanti I, Gulino A: Thrombospondin-1 is a mediator of the neurotypic differentiation induced by EGF in thymic epithelial cells. Exp Cell Res 248: 79-86, 1999.
Giannini G, Di Marcotullio L, Ristori E, Zani M, Crescenzi M, Scarpa S, Piaggio G, Vacca A, Peverali FA, Diana F, Screpanti I, Frati L, Gulino A: HMGI(Y) and HMGI-C genes are expressed in neuroblastoma cell lines and tumors and affect retinoic acid responsiveness. Cancer Res 59: 2484-2492, 1999.
Turco A, Scarpa S, Coppa A, Baccheschi G, Palumbo C, Leonetti C, Zupi G, Colletta G: Increased TGFbeta type II receptor expression suppresses the malignant phenotype and induces differentiation of human neuroblastoma cells. Exp Cell Res. 225: 77-85, 2000.
Scarpa S, Giuffrida A, Palumbo C, Coletti A, Cerrito MG, Vasaturo F, Sinibaldi P, Simonelli L, Procopio A, Modesti A. Retinoic acid inhibits fibronectin and laminin synthesis and cell migration of human pleural mesothelioma in vitro. Oncol Reports 9: 205-209, 2002.
Santini D, Vincenzi B, Tonini G, Scarpa S, Baldi A. Zoledronic acid exhibits inhibitory effects on osteoblastic and osteolytic metastases of prostate cancer. Clin Cancer Res 9: 3215-3216, 2003.
Santini D, Vespasiani Gentilucci U, Vincenzi B, Picardi A, Vasaturo F, La Cesa A, Onori N, Scarpa S, Tonini G. The antineoplastic role of biphosphonates: from basic research to clinical evidence. Ann Oncol 14: 1468-1476, 2003.
Gradilone A, Gazzaniga P, Ribuffo D, Scarpa S, Cigna E, Vasaturo F, Bottoni U, Innocenzi D, Calvieri S, Scuderi N, Frati L, Agliano AM. Survivin, bcl2, bax and bclX gene expression in sentinel lymph nodes from melanoma patients. J Clin Oncol 21: 306-312, 2003.
Biondi-Zoccai GL, Abbate A, Vasaturo F, Scarpa S, Santini D, Leone AM, Parisi Q, de Giorgio F, Bussani R, Silvestri F, Baldi F, Biasucci LM, Baldi A. Increased apoptosis in remote non-infarcted myocardium in multivessel coronary disease. Int J Cardiol, 94: 105-110, 2004.
Baldi A, Santini D, Vasaturo F, Santini M, Vicidomini G, Di Marino M, Esposito V, Groeger AM, Vincenzi B, Tonini G, Piccoli M, Baldi F, Scarpa S. Prognostic significance of cyclooxygenase-2 (COX-2) and cell cycle inhibitors p21 and p27 expression in human pleural malignant mesothelioma. Thorax 59: 428-433, 2004.
Salvioli R, Scarpa S, Ciaffoni F, Tatti M, Ramoni C, Vanier MT, Vaccaro AM. Glucosylceramidase mass and subcellular localization are modulated by cholesterol in Niemann-Pick disease type C. J Biol Chem 279: 17674- 17680, 2004.
Vasaturo F, Malacrino C, Sallusti E, Coppotelli G, Birarelli P, Giuffrida A, Albonici L, Simonelli L, Modesti A, Modesti M, Scarpa S: Role of extracellular matrix in regulation of staurosporine-induced apoptosis in breast cancer cells. Oncol Report 13: 745-750, 2005.
Salvioli R, Tatti M, Scarpa S, Moavero SM, Ciaffoni F, Felicetti F, Kaneski CR, Brady RO, Vaccaro AM. The N370S mutation affects the capacity of glucosylceramidase to interact with anionic phospholipid-containing membranes and Saposin C. Biochem J 390: 95-103, 2005.
Salvioli R, Tatti M, Scarpa S, Moavero SM, Ciaffoni F, Felicetti F, Kaneski CR, Brady RO, Vaccaro AM. The N370S mutation affects the capacity of glucosylceramidase to interact with anionic phospholipid-containing membranes and Saposin C. Biochem J 390: 95-103, 2005.
Vasaturo F, Sallusti E, Gradilone A, Malacrino C, Nardo T, Avagnano G, Agliano AM, Granato T, Vincenzi B, Coppotelli G, Marzullo A, Soda G, Modesti M, Scarpa S. Comparison of extracellular matrix and apoptotic markers between benign lesions and carcinomas in human breast. Int J Oncol. 27: 1005-11, 2005.
Parisi Q, Biondi-Zoccai GG, Abbate A, Santini D, Vasaturo F, Scarpa S, Bussani R, Leone AM, Petrolini A, Silvestri F, Biasucci LM, Baldi A. Hypoxia inducible factor-1 expression mediates myocardial response to ischemia late after acute myocardial infarction. Int J Cardiol. 99: 337-339, 2005.
Abbate A, Bussani R, Biondi-Zoccai GG, Santini D, Vasaturo F, Scarpa S, Severino A, Biasucci LM, Baldi A. Infarct related artery occlusion, tissue markers of ischemia and increased apoptosis in the peri-infarct viable myocardium. Eur Heart J 26: 2039-2045, 2005.
Santini D, Vincenzi B, Tonini G, Scarpa S, Vasaturo F, Malacrino C, Vecchio F, Borzomati D, Valeri S, Coppola R, Nuzzo G, Picciocchi A. Cyclooxygenase-2 overexpression is associated with a poor out come in resecate ampullary cancer patients. Clin Cancer Res 11: 3784-3789, 2005.
Santini D, Caraglia M, Vincenzi B, Holen I, Scarpa S, Budillon A, Tonini G. Mechanisms of disease: preclinical reports of antineoplastic synergistic action of bisphosphonates. Nature Clin Pract Oncol 3: 325-338, 2006.
Abbate A, Limana F, Capogrossi MC, Santini D, Biondi-Zoccai GG, Scarpa S, Germani A, Straino S, Severino A, Vasaturo F, Campioni M, Liuzzo G, Crea F, Vetrovec GW, Biasucci LM, Baldi A: Cyclo-oxygenase 2 inhibition reduces apoptosis in acute myocardial infarction. Apoptosis 11: 1061-3, 2006.
Abbate A, Scarpa S, Santini D, Palleiro J, Vasaturo F, Miller L, Morales C, Vetrovec GW, Baldi A: Myocardial expression of servivi, an apoptosis inhibitor, in aging and heart failure. An experimental study in the spontaneously hypertensive rat. Int J Cardiol 111: 371-376, 2006.
Abbate A, Morales C, De Falco M, Fedele V, Biondi Zoccai GG, Santini D, Palleriro J, Scarpa S, Vasaturo F, Liuzzo G, Severino A, Baldi F, Crea F, Biasucci LM, Vetrovec GW, Gelpi RJ, Baldi A. Ischemia and apoptosis in an animal model of permanent infarct-related artery occlusion. Int J Cardiol 121: 109-111, 2007.
Gradilone A, Gazzaniga P, Cigna E, Vasaturo F, Vincenzi B, Gandini O, Silvestri I, Ribuffo D, Scarpa S, Scuderi N, Agliano AM. Fibronectin and laminin expression in sentinel lymph nodes of patients with malignant melanoma. Br J Dermatol.157: 398-401, 2007.
Gazzaniga P, Silvestri I, Gradilone A, Scarpa S, Morrone S, Gandini O, Gianni W, Frati L, Agliano AM. Gemcitabine- induced apoptosis in 5637 cell line: an in-vitro model for high-risk superficial bladder cancer. Anti-cancer Drug 18: 179-85, 2007.
Salvioli R, Ricci-Titiani L, Tatti M, Scarpa S, De Maria R, Vaccaro AM: The secretion and maturation of prosaposin and procathepsin D are blocked in embryonic progenitor cells. BBA 1783: 1480-1489, 2008.
Vaccaro AM, Motta M, Tatti M, Scarpa S, Masuelli L, Bhat M, Vanier MT, Salvioli R: Saposin C mutations in Gaucher disease patients resulting in lisosoma lipid accumulation, saposin C deficency but normal prosaposin processing and sorting. Hum Mol Genetics 19: 2987-2997, 2010.
Tatti M, Motta M, Di Bartolomeo S, Scarpa S, Cianfanelli V, Cecconi F, Salvioli R. Reduced chatepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C deficient fibroblasts. Hum Mol Genet 21: 6159-5173, 2012.
Vicinanza R, Coppotelli G, Malacrino C, Nardo T, Buchetti B, Lenti L, Celi F, Scarpa S. Oxidized-LDL impair endothelial function by inhibiting non-genomic action of thyroid hormone-mediated nitric oxide production in human endothelial cells. Thyroid 23: 231-238, 2013.
Silvestri I, Cattarino S, Agliano A, Nicolazzo C, Scarpa S, Salciccia S, Frati L, Gentile V, Sciarra A. Effect of Serenoa repens (Permixon®) on the expression of inflammation-related genes: analysis in primary cell cultures of human prostate carcinoma. J Inflamm 10: 11. doi: 10.1186/1476-9255-10-11, 2013.
Vasaturo F, Solai F, Malacrino C, Nardo T, Vincenzi B, Modesti M, Scarpa S. Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients. Oncol Lett. 5: 316-320, 2013.
De Iuliis F, Salerno G, Taglieri L, Vicinanza R, Lanza R, Scarpa S. Elderly woman with triple-negative metastatic breast cancer successfully treated with metronomic capecitabine. Anticancer Res. 34: 4287-91, 2014.
Nardo T, Micalizzi G, Vicinanza R, De Iuliis F, Taglieri L, Scarpa S. Adhesion to type V collagen enhances staurosporine-induced apoptosis of adrenocortical cancer cells. Tumour Biol. 35: 9949-55. doi: 10.1007/s13277-014-
De Iuliis F, Salerno G, Taglieri L, Vicinanza R, Lanza R, Scarpa S. Elderly woman with triple-negative metastatic breast cancer successfully treated with metronomic capecitabine. Anticancer Res. 34: 4287-91, 2014.
De Iuliis F, Amoroso L, Taglieri L, Vendittozzi S, Blasi L, Salerno G, Lanza R, Scarpa S. Chemotherapy of rare skin adnexal tumors: a review of literature. Anticancer Res. 34: 5263-8, 2014.
Nardo T, Micalizzi G, Vicinanza R, De Iuliis F, Taglieri L, Scarpa S. Adhesion to type V collagen enhances staurosporine-induced apoptosis of adrenocortical cancer cells. Tumour Biol. 35: 9949-55. doi: 10.1007/s13277-014- 2281-6, 2014.
De Iuliis F, Taglieri L, Amoroso L, Vendittozzi S, Blasi L, Salerno G, Lanza R, Scarpa S. Prevention of osteonecrosis of the jaw in patients with bone metastases treated with bisphosphonates. Anticancer Res. 34: 2477-80, 2014.
Bianchi E, Taurone S, Bardella L, Signore A, Pompili E, Sessa V, Chiappetta C, Fumagalli L, Di Gioia C, Pastore FS, Scarpa S, Artico M. Involvement of pro-inflammatory cytokines and growth factors in the pathogenesis of Dupuytren's contracture: a novel target for a possible future therapeutic strategy? Clin Sci 129: 711-20. doi: 10.1042/CS20150088, 2015.
De Iuliis F, Salerno G, Taglieri L, Scarpa S. Are pharmacogenomic biomarkers an effective tool to predict taxane toxicity and outcome in breast cancer patients? Literature review. Cancer Chemother Pharmacol. 76: 679-90. doi: 10.1007/s00280-015-2818-4, 2015.
De Iuliis F, Taglieri L, Salerno G, Lanza R, Scarpa S. Taxane induced neuropathy in patients affected by breast cancer: Literature review. Crit Rev Oncol Hematol. 96: 34-45. doi: 10.1016/j.critrevonc.2015.04.011, 2015.
Tatti M, Motta M, Scarpa S, Di Bartolomeo S, Cianfanelli V, Tartaglia M, Salvioli R. BCM-95 and B-cyclodextrin reverse autophagy dysfunction and deplete stored lipids in Sap C-deficent fibroblasts. Hum Mol Genet. 24: 4198-211. doi: 10.1093/hmg/ddv153, 2015.
De Iuliis F, Salerno G, Taglieri L, Lanza R, Scarpa S. On and off metronomic oral vinorelbine in elderly women with advanced breast cancer. Tumori 101: 30-5. doi: 10.5301/tj.5000207, 2015.
De Iuliis F, Lanza R, Scarpa S. Are we ready to change clinical practice after the 'soft and text' results? Future Oncol. 11: 2857-2860, 2015.
De Monte C, Carradori S, Secci D, D Ascenzio M, Guglielmi P, Mollica A, Morrone S, Scarpa S, Agliano AM, Giantulli S, Silvestri I. Synthesis and pharmacological screening of a large library of 1,3,4-thiadiazolines as innovative therapeutic tools for the treatment of prostate cancer and melanoma. European Journal of Medicinal Chemistry 105: 245-62, 2015. doi: 10.1016/j.ejmech.2015.10.023.
De Iuliis F, Salerno G, Giuffrida A, Milana B, Taglieri L, Rubinacci G, Giantulli S, Terella F, Silvestri I, Scarpa S. Breast cancer cells respond differently to docetaxel depending on their phenotype and on survivin upregulation. Tumour Biol. 37: 2603-2611, 2016. doi: 10.1007/s13277-015-4075-x.
De Iuliis F, Salerno G, Taglieri L, De Biase L, Lanza R, Cardelli P, Scarpa S. Serum biomarkers evaluation to predict chemotherapy-induced cardiotoxicity in breast cancer patients. Tumour Biol. 37: 3379-3387, 2016. doi: 10.1007/s13277-015-4183-7.
De Iuliis F, Taglieri L, Salerno G, Giuffrida A, Milana B, Giantulli S, Carradori S, Silvestri I, Scarpa S. The kinesin Eg5 inhibitor K858 induces apoptosis but also survivin-related chemoresistance in breast cancer cells. Invest. New Drugs 34: 399-406, 2016. doi: 10.1007/s10637-016-0345-8
Corvino R, De Iuliis F, D Aniello D, Cefali K, Lanza R, Scarpa S. Novel schedule for treatment of inflammatory breast cancer. Open J. Clin. Med. Case Reports. 2 (20): 1175, 2016. ISSN 2379-1039.
Corvino R, De Iuliis F, D Aniello D, Cefali K, Ferraro E, Lamazza A, Lanza R, Scarpa S. Long-lasting stent placement in an elderly advanced ovarian cancer patient. Oncol Res Treat. 39: 146-8, 2016. doi: 10.1159/000444273
De Iuliis F, Mandolini PL, Cursano MC, Menghi A, Salerno G, Taglieri L, Curatolo P, Lanza R, Scarpa S. Nodal and cutaneous Kaposi s sarcoma. G Ital Dermatol Venereol. 151: 215-216, 2016.
De Iuliis F, Vendittozzi S, Taglieri L, Salerno G, Lanza R, Scarpa S. Metronomic chemotherapy preserves quality of life ensuring efficacy in elderly advanced non small cell lung cancer patients. Int J Cancer Clin Res. 3: 46, 2016. ISSN: 2378-3419.
De Iuliis F, Salerno G, Corvino R, D Aniello D, Cefali K, Taglieri L, Lanza R, Scarpa S. Anthracycline-free neoadjuvant chemotherapy ensures higher rates of pathologic complete response in breast cancer. Clin Breast Cancer 17: 34-40, 2017. doi: 10.1016/j.clbc.2016.06.010.
De Iuliis F, Salerno G, Taglieri L, Lanza R, Cardelli P, Scarpa S. Circulating neuregulin-1 and galectin-3 can be prognostic markers in breast cancer. Int J Biol Markers 32: 333-336. doi: 10.5301/ijbm.5000262, 2017.
Taglieri L, De Iuliis F, Giuffrida A, Giantulli S, Silvestri I, Scarpa S. Resistance to the mTOR inhibitor everolimus can be reversed by the downregulation of survivin in breast cancer cells. Oncol Lett. 14: 3832-3838. doi: 10.3892/ol.2017.6597, 2017.
Taglieri L, Nardo T, Vicinanza R, Ross JM, Scarpa S, Coppotelli G. Thyroid hormone regulates fibronectin expression through the activation of the hypoxia inducible factor 1. Biochem Biophys Res Commun 493: 1304-1310, doi: 10.1016/j.bbrc.2017.09.169, 2017.
Taglieri L, Rubinacci G, Giuffrida A, Carradori S, Scarpa S. The kinesin Eg5 inhibitor K858 induces apoptosis and reverses the malignant invasive phenotype in human glioblastoma cells. Invest New Drugs 36: 28-35. doi: 10.1007/s10637-017-0517-1, 2018.
Giantulli S,De Iuliis F, Taglieri L, Carradori S, Menichelli G, Morrone S, Scarpa S, Silvestri I. Growth arrest and apoptosis induced by kinesin Eg5 inhibitor K858 and by its 1,3,4-thiadiazoline analogue in tumor cells. Anti-cancer Drugs 29: 674-681. doi: 10.1097/CAD.0000000000000641, 2018.
Silvestri I, Tortorella E, Giantulli S, Scarpa S, Sciarra A. Immunotherapy in prostate cancer: Recent advances and future directions. Europ. Medical Journal 7: 51-61, 2019.
Sciarra A, Gentilucci A, Silvestri I, Salciccia S, Scarpa S, Cattarino S, Gatto A, Frantellizzi V, Von Heland M, Ricciuti GP, Del Giudice F, Maggi M. Androgen receptor variant 7 (AR-V7) in sequencing therapeutic agents for castration resistant prostate cancer: a critical review. Medicine 98: 19 (e15608). doi: 10.1097/MD.0000000000015608, 2019.
Taurone S, Spoletini M, Chiappetta C, Di Gioia C, Carletti R, Greco A, Agostinelli E, Ralli M, Giangaspero F, Artico M, Pastore MS, Scarpa S, Gobbi P, Di Liddo R. Brain gliomas and growth factors: immunohistochemical, immunofluorescence, flow cytometry and RT-PCR profile in pediatric age. Journal of Biological regulators and homeostatic agents 33: 1451-1463, 2019.
Domenici F, Capocefalo A, Brasili F, Bedini A, Giliberti C, Palomba R, Silvestri I, Scarpa S, Morrone S, Paradossi G, Frogley M, Cinque G. Ultrasound delivery of surface enhanced InfraRed absorption active gold-nanoprobes into fibroblast cells: a biological study via Synchrotron-based InfraRed microanalysis at single cell level. Scientific Reports 9: 11845. doi: 10.1038/s41598-019-48292-0, 2019.
Stazi G, Taglieri L, Nicolai A, Romanelli A, Fioravanti R, Morrone S, Sabatino M, Ragno R, Taurone S, Nebbioso S, Carletti R, Artico M, Valente S, Scarpa S, Mai A. Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype. Clinical Epigenetics 11: 173. doi: 10.1186/s13148-019-0763-5, 2019.
Taglieri L, Saccoliti F, Nicolai A, Peruzzi G, Madia VN, Tudino V, Messore A, Di Santo R, Artico M, Taurone S, Salvati M, Costi R, Scarpa S. Discovery of a pyrimidine compound endowed with antitumor activity. Invest. New Drugs 38: 39-49. doi: 10.1007/s10637-019-00762-y, 2020.
Sciarra A, Maggi M, Salciccia S, Nicolai A, Tortorella E, Giantulli S, Magliocca F, Silvestri I, Taglieri L, Cattarino S, Scarpa S. Tissue expression of androgen receptor splice variant 7 at radical prostatectomy predicts risk of progression in untreated non-metastatic prostate cancer. Oncology, doi: 10.1159/000512445, 2021.
Madia VM, Nicolai A, Messore A, De Leo A, Ialongo D, Tudino V, Saccoliti F, De Vita D, Scipione L, Artico M, Taurone S, Taglieri L, Di Santo R, Scarpa S, Costi. Design, synthesis and biological evaluation of new pyrimidine derivatives as anticancer agents. Molecules, 26, 771. doi: 10.3390/molecules26030771, 2021.