Catalogo dei Corsi di studio

DIPARTIMENTO DI Scienze Anatomiche, Istologiche, Medico-Legali e dell'Apparato Locomotore: Sezione di Istologia ed Embriologia Medica
CURRICULUM DIDATTICO-SCIENTIFICO DEL/LA PROF.

DATI PERSONALI
Nome e Cognome
Rosemari Brigitte Heyn Salinas

Luogo e data di nascita:
Stato Civile: single
Dipartimento
Dept. of Anatomic, Histologic, Forensic and Orthopaedic Sciences

Indirizzo
Via Alfonso Borelli, 50.
00161 Rome

Telefono uff./lab. +39-0649918012
Fax
E-mail rose.heyn@uniroma1.it

Settore Scientifico-Disciplinare: BIO-16
Orario di Ricevimento: Mondays 9:00-12:00, by e-mail appointment and Messenger

ATTUALE POSIZIONE
University Researcher (Assistant Professor) of human anatomy

CARRIERA E TITOLI

Veterinary Medical Doctor (2000, University of Messina, Italy)
Doctorate (Ph.D.) in Human Anatomy (2000, Sapienza University of Rome, Italy)
Magister in Reproductive Biology (1992, Universidad de Chile, Santiago, Chile)
Veterinary Medical Doctor (1988, Universidad de Chile, Santiago, Chile)
Each degree included a biennial experimental Thesis

ATTIVITA DIDATTICA

Responsible of Sapienza University of Rome s Sectra digital anatomic table, placed at Laboratorio di Simulazione e Formazione Medica Avanzata (Policlinico Umberto I, Obstetrics Clinic, ground floor)
Teaching of human anatomy to health sciences (Nursing, in English; one semester, I year)
Teaching of human anatomy to CLM in Medical Biotechnology (one semester, IV year)
Teaching of human anatomy to CLM in Medicine and Surgery (three semesters, I-II years)
Teaching of human anatomy to postgraduate medical and biomedical students (Master di I livello in Citopatologia diagnostica e screening di popolazione, Sant Andrea University Hospital)
E-learning on advanced teaching methodologies (MATAM, Master di II Livello in Teledidattica applicata alla Scienze della Salute e ICT in Medicina, Unità di Teledidattica Giovanni D Addona , Sapienza University of Rome)
E-learning and elaboration of video tutorials on the use of Art for enhancing medical clinical skills (the material is uploaded to either an institutional channel of YouTube in collaboration with Unità di Teledidattica Giovanni D Addona , Sapienza University of Rome, as well as in a social network page created ad hoc for this aim; the page is on Facebook and is entitled: Arte e Anatomia: l arte di osservare )

ATTIVITA SCIENTIFICA

- Research on human reproduction (main field: transmission and scanning electron microscopy; male and female reproductive tracts) and e-learning on advanced teaching methodologies
- Has participated in over 100 national and international congresses as contributor and
invited speaker
- XXII Congreso de Anatomía del Cono Sur [XXII Congress of Anatomy of South America] Enseñanza e Investigación en Morfología en Tiempos de COVID-19 [Teaching and Research on Morphology During COVID-19]. First Virtual South American Congress in History on Anatomy]. VI Congreso Regional de Morfología - II International Congress on Anatomical Techniques - II Jornadas de la Asociación Panamericana de Anatomía. 23-27th November 2020 Temuco, Chile. Transmitted in vivo through the channel Zoom UFRO Channel YouTube APA. Invited speaker (invitation of Prof. Dr. Nicolás E. Ottone, President of II International Congress on Anatomical Techniques) with the online video conference (45 minutes) entitled: Enseñanza de Anatomía Clínica en Tiempos de COVID-19: Nuestra Experiencia [Teaching of Clinical Anatomy During COVID-19: Our Experience].
- Sectra Education User Meeting 2019 Edition that took place in Stockholm City, Sweden, on 18th and 19th of June 2019 at Karolinska Institute Solna Campus
- Invited speaker in the meeting Advanced technology in dermatology with the lecture
Aspects of skin electron microscopy (December 1st 2016, organized by Severino
Persechino, Sant Andrea Hospital, Rome)
- Participant in the e-course on General formation of workers (4 h, completed on May 26th 2016, Sapienza University of Rome)
- Participant in the theoretical-practical training course on Scanning Electron Microscopy on the use of the ZEISS EVO 40XVP system (April 8th 2015, ASSING, Rome)
- Invited speaker in the meeting Embryological basis of the surgical technique held in the Congress Centre Raffaele Bastianelli (April 9-10th 2013, IFO- Istituti Fisioterapici Ospitalieri, Rome)
- Has been member of the organizing and scientific committees in several international
congresses on morphological sciences and human anatomy
- Is member of the Italian Society of Anatomy and Histology (SIAI) since 1995, taking active part as speaker in the annual congresses of the Society
- Is member Italian Society of Microscopical Sciences (SISM) since 2003; and European Society of Microscopical Sciences (EMS) since 2003
- Is member of the College of Teachers of the Doctorate programme in Anatomy, Plastic
Surgery, Dermatology, and has collaborated as tutor in the elaboration of Theses; is also
member of the College of Teachers of the Doctorate programme in Biotechnology of Human
Reproduction
- From 2008 to 2012 she was Referee and Member of the editorial committee of the international on-line scientific journal Reproductive Biology & Endocrinology (Editor-in-Chief: Prof. Antonin Bukovsky) and Deputy Editor May 2008)
- She is member of the Evaluation Board in the Faculty of 1000 Medicine Project F1000- in the Faculty Diabetes and Endocrinology, Section Reproductive Endocrinology and infertility https://f1000.com/prime/thefaculty/member/7123524731404722
. She has received three times the Award F1000 Faculty Member of the Year (2015, 2016, 2019).
- Since 2015 she is member of the Mentoring Committee of the Faculty of Medicine and Psychology (Sant Andrea Hospital, Sapienza University of Rome, Rome)
- References can be asked to:
- Prof. Ugo Muglia (Università degli studi di Messina): ugo.muglia@unime.it
- Prof. Guido Macchiarelli (Università di L Aquila): guido.macchiarelli@cc.univaq.it
- Prof. Osamu Ohtani (Tokyo Medical University, Japan): osamu.ohtani@oasis.ocn.ne.jp
- Prof. Tatsuo Ushiki (Niigata University Graduate School of Medical and Dental Sciences,
Japan): t-ushiki@med.niigata-u.ac.jp
- Prof. Pedro Esponda (Centro de Investigaciones Biológicas (CSIC, Spain):
esponda@cib.csic.es
- Prof. Isaura Prado (University of Maringá, Brazil): immprado@uem.br

ATTIVITA ASSISTENZIALE (per i settori in cui è prevista)

PUBBLICAZIONI SCIENTIFICHE
A. Peer reviewed publications of Rosemarie Heyn

Habiba, M., Heyn, R., Bianchi, P., Brosens, I., Benagiano, G.
The development of the human uterus: Morphogenesis to menarche
(2021) Human Reproduction Update, 27 (1), pp. 1-26.
Document Type: Review
Publication Stage: Final
Source: Scopus

Vizza, E., Petrozza, V., Porta, N., Certelli, C., Battaglione, E., Corrado, G., Familiari, G., Heyn, R.
Primary vaginal leiomyosarcoma: A case report with complete morphological, immunohistochemical
and ultrastructural study
(2020) Taiwanese Journal of Obstetrics and Gynecology, 59 (2), pp. 314-317.
DOI: 10.1016/j.tjog.2020.01.023
Document Type: Article
Publication Stage: Final
Access Type: Open Access
Source: Scopus

Vitalone, A., Di Sotto, A., Mammola, C.L., Heyn, R., Miglietta, S., Mariani, P., Sciubba, F., Passarelli,
F., Nativio, P., Mazzanti, G.
Phytochemical analysis and effects on ingestive behaviour of a Caralluma fimbriata extract
(2017) Food and Chemical Toxicology, 108, pp. 63-73. Cited 7 times.
DOI: 10.1016/j.fct.2017.07.027
Document Type: Article
Publication Stage: Final
Source: Scopus

Familiari, G., Relucenti, M., Heyn, R., Baldini, R., D'Andrea, G., Familiari, P., Bozzao, A., Raco, A.
The value of neurosurgical and intraoperative magnetic resonance imaging and diffusion tensor
imaging tractography in clinically integrated neuroanatomy modules: A cross-sectional study
(2013) Anatomical Sciences Education, 6 (5), pp. 294-306. Cited 4 times.
DOI: 10.1002/ase.1349
Document Type: Article
Publication Stage: Final
Source: Scopus

Lukic, A., Iannaccio, S., Heyn, R., Villani, S., Nobili, F., Giarnieri, E., Mancini, R., Moscarini, M.,
Giovagnoli, M.R.
Satisfactory sampling in cytological cervical diagnosis: Comparison between a conventional and a
new sampling device
(2013) Anticancer Research, 33 (3), pp. 917-922. Cited 2 times.
Document Type: Article
Publication Stage: Final
Source: Scopus

Caggiati, A., Franceschini, M., Heyn, R., Rosi, C.
Skin erythrodiapedesis during chronic venous disorders
(2011) Journal of Vascular Surgery, 53 (6), pp. 1649-1653. Cited 10 times.
Document Type: Article
Publication Stage: Final
Access Type: Open Access
Source: Scopus

Heyn, R., Relucenti, M., Petruzziello, L., Franchitto, G., Pastore, A., Palleschi, G., Carbone, A., Rago,
R., Petrozza, V., Familiari, G.
Non-mosaic, non-azoospermic Klinefelter's syndrome in a young man with bilateral varicocele
(2011) Journal of Endocrinological Investigation, 34 (6), pp. 485-486.
DOI: 10.1007/BF03346717
Document Type: Letter
Publication Stage: Final
Source: Scopus

Familiari, G., Heyn, R., Petruzziello, L., Relucenti, M.
A method to visualize the micro architecture of glycoprotein matrices with scanning electron microscopy
(2010) Scanning Electron Microscopy for the Life Sciences, 9780521195997, pp. 165-178. Cited 1
time.
Document Type: Book Chapter
Publication Stage: Final
Source: Scopus

Relucenti, M., Heyn, R., Petruzziello, L., Pugliese, G., Taurino, M., Familiari, G.
Detecting microcalcifications in atherosclerotic plaques by a simple trichromic staining method for
epoxy embedded carotid endarterectomies
(2010) European Journal of Histochemistry, 54 (3), pp. 143-147. Cited 11 times.
DOI: 10.4081/ejh.2010.e33
Document Type: Article
Publication Stage: Final
Access Type: Open Access
Source: Scopus

Barberini, F., Bruner, E., Cartolari, R., Franchitto, G., Heyn, R., Ricci, F., Manzi, G.
An unusually-wide human bregmatic Wormian bone: Anatomy, tomographic description, and possible
significance
(2008) Surgical and Radiologic Anatomy, 30 (8), pp. 683-687. Cited 24 times.
Document Type: Article
Publication Stage: Final
Source: Scopus

Familiari, G., Heyn, R., Relucenti, M., Sathananthan, H.
Structural changes of the zona pellucida during fertilization and embryo development
(2008) Frontiers in Bioscience, 13 (17), pp. 6730-6751. Cited 30 times.
DOI: 10.2741/3185
Document Type: Article
Publication Stage: Final
Source: Scopus

Barberini, F., Makabe, S., Franchitto, G., Correr, S., Relucenti, M., Heyn, R., Familiari, G.
Ultrastructural dynamics of the human endometrium from 14 to 22 weeks of gestation
(2007) Archives of Histology and Cytology, 70 (1), pp. 21-28. Cited 4 times.
DOI: 10.1679/aohc.70.21
Document Type: Article
Publication Stage: Final
Access Type: Open Access
Source: Scopus

Caggiati, A., Rosi, C., Heyn, R., Franceschini, M., Acconcia, M.C.
Age-related variations of varicose veins anatomy
(2006) Journal of Vascular Surgery, 44 (6), pp. 1291-1295. Cited 42 times.
DOI: 10.1016/j.jvs.2006.07.040
Document Type: Article
Publication Stage: Final
Access Type: Open Access
Source: Scopus

Familiari, G., Heyn, R., Relucenti, M., Nottola, S.A., Sathananthan, A.H.
Ultrastructural Dynamics of Human Reproduction, from Ovulation to Fertilization and Early Embryo
Development1
(2006) International Review of Cytology, 249, pp. 53-141. Cited 33 times.
Document Type: Review
Publication Stage: Final
Source: Scopus

Nottola, S.A., Heyn, R., Camboni, A., Correr, S., Macchiarelli, G.
Ultrastructural characteristics of human granulosa cells in a coculture system for in vitro fertilization
(2006) Microscopy Research and Technique, 69 (6), pp. 508-516. Cited 27 times.
DOI: 10.1002/jemt.20309
Document Type: Article
Publication Stage: Final
Source: Scopus

Familiari, G., Relucenti, M., Heyn, R., Micara, G., Correr, S.
Three-dimensional structure of the zona pellucida at ovulation
(2006) Microscopy Research and Technique, 69 (6), pp. 415-426. Cited 52 times.
DOI: 10.1002/jemt.20301
Document Type: Review
Publication Stage: Final
Source: Scopus

Barberini, F., Ripani, M., Heyn, R., Di Nitto, V., Magnosi, F., Familiari, G.
A singular pancreatico-colic artery: Anatomical report and clinical implications
(2006) Surgical and Radiologic Anatomy, 28 (3), pp. 328-331. Cited 3 times.
Document Type: Article
Publication Stage: Final
Source: Scopus

Correr, S., Makabe, S., Heyn, R., Relucenti, M., Naguro, T., Familiari, G.
Microplicae-like structures of the fallopian tube in postmenopausal women as shown by electron
microscopy
(2006) Histology and Histopathology, 21 (1-3), pp. 219-226. Cited 12 times.
Document Type: Article
Publication Stage: Final
Source: Scopus

Vizza, E., Correr, S., Barberini, F., Heyn, R., Bianchi, S., Macchiarelli, G.
3-D ultrastructural distribution of collagen in human placental villi at term in relation to vascular tree
(2005) Journal of Reproduction and Development, 51 (4), pp. 433-443. Cited 4 times.
DOI: 10.1262/jrd.17022
Document Type: Article
Publication Stage: Final
Access Type: Open Access
Source: Scopus

Relucenti, M., Heyn, R., Correr, S., Familiari, G.
Cumulus oophorus extracellular matrix in the human oocyte: A role for adhesive proteins
(2005) Italian Journal of Anatomy and Embryology, 110 (2 SUPPL. 1), pp. 219-224. Cited 20 times.
Document Type: Conference Paper
Publication Stage: Final
Source: Scopus

Heyn, R., Makabe, S., Correr, S., Naguro, T., Familiari, G.
Pietro Motta's latest studies on the microanatomy of menopause: Revised concepts on the beauty of
aging
(2005) Italian Journal of Anatomy and Embryology, 110 (2 SUPPL. 1), pp. 239-243. Cited 3 times.
Document Type: Conference Paper
Publication Stage: Final
Source: Scopus

Motta, P.M., Heyn, R., Makabe, S.
Three-dimensional microanatomical dynamics of the ovary in postreproductive aged women
(2002) Fertility and Sterility, 78 (2), pp. 360-370. Cited 20 times.
Document Type: Article
Publication Stage: Final
Source: Scopus

Heyn, R., Makabe, S., Motta, P.M.
Ultrastructural morphodynamics of human Sertoli cells during testicular differentiation.
(2001) Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 106
(2 Suppl 2), pp. 163-171. Cited 3 times.
Document Type: Review
Publication Stage: Final
Source: Scopus
Vizza, E., Goranova, V., Heyn, R., Correr, S., Motta, P.M.
Extracellular fibrillar matrix architecture of human placental villi at term.
(2001) Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 106
(2 Suppl 2), pp. 317-323. Cited 4 times.
Document Type: Article
Publication Stage: Final
Source: Scopus

Motta, P.M., Heyn, R., Vizza, E.
Imaging of the endometrium: New methods [Article@Imagerie de l'endometre: Nouvelles
explorations]
(2000) Reproduction Humaine et Hormones, 13 (6), pp. 639-643.
Document Type: Conference Paper
Publication Stage: Final
Source: Scopus

Motta, P.M., Nottola, S.A., Makabe, S., Heyn, R., Jansen, R.
Mitochondrial morphology in human fetal and adult female germ cells
(2000) Human Reproduction, 15 (SUPPL. 2), pp. 129-147. Cited 184 times.
Document Type: Conference Paper
Publication Stage: Final
Access Type: Open Access
Source: Scopus

Heyn, R., Makabe, S., Motta, P.M.
Ultrastructural dynamics of human testicular cords from 6 to 16 weeks of embryonic development.
Study by transmission and high resolution scanning electron microscopy.
(1998) Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 103
(4 Suppl 1), pp. 17-29. Cited 8 times.
Document Type: Article
Publication Stage: Final
Source: Scopus
Vizza, E., Goranova, V., Correr, S., Heyn, R., Motta, P.M.
The extracellular matrix of normal human placental villi at term: a scanning electron microscopy
study.
(1998) Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 103
(4 Suppl 1), pp. 301-307. Cited 1 time.
Document Type: Article
Publication Stage: Final
Source: Scopus

Heyn, R., Muglia, U., Motta, P.M.
Microarchitecture of the cat testis with special reference to leydig cells: A three-dimensional study by
alkali maceration method and scanning electron microscopy
(1997) Archives of Andrology, 39 (2), pp. 135-145. Cited 1 time.
Document Type: Article
Publication Stage: Final
Source: Scopus

Makabe, S., Heyn, R., Motta, P.M.
Ultrastructure of human Sertoli cells at early gonad embryogenesis [Article@Ultrastructure des
cellules de Sertoli humaines aux stades embryonnaires precoces de la differenciation gonadique]
(1997) Andrologie, 7 (3), pp. 327-335.
DOI: 10.1007/BF03034550
Document Type: Article
Publication Stage: Final
Access Type: Open Access
Source: Scopus

Watanabe, I., Nagata, T., Jin, C., Heyn, R., Motta, P.M.
Development of mouse submandibular gland studied by field emission scanning electron microscopy.
(1997) Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 102
(1), pp. 49-57. Cited 2 times.
Document Type: Article
Publication Stage: Final
Scopus

Heyn, R., Muglia, U., Vizza, E., Motta, P.M.
The collagen skeleton of the cat testis. A scanning electron microscopy study after 2N-NaOH
maceration.
(1996) Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 101
(3), pp. 133-140. Cited 2 times.
Document Type: Article
Publication Stage: Final
Source: Scopus

Goranova, V., Vizza, E., Correr, S., Heyn, R., Motta, P.M.
Collagen fibrillar skeleton in pregnant rabbit endometrium at term: A SEM study after NaOH
maceration
(1996) Archives of Histology and Cytology, 59 (2), pp. 127-135. Cited 4 times.
DOI: 10.1679/aohc.59.127
Document Type: Article
Publication Stage: Final
Access Type: Open Access
Source: Scopus

Watanabe, I., Heyn, R., Motta, P.M.
Scanning electron microscopy study of the palatine salivary glands of rabbits.
(1995) Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 100
Suppl 1, pp. 375-383. Cited 3 times.
Document Type: Article
Publication Stage: Final
Source: Scopus

Makabe, S., Naguro, T., Heyn, R., Motta, P.M.
Ultrastructure of human Leydig cells at early gonadal embryogenesis.
(1995) Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 100
Suppl 1, pp. 525-533. Cited 8 times.
Document Type: Article
Publication Stage: Final
Source: Scopus

Vizza, E., Correr, S., Goranova, V., Heyn, R., Muglia, U., Papagianni, V.
The collagen fibrils arrangement in the Wharton's jelly of full-term human umbilical cord.
(1995) Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 100
Suppl 1, pp. 495-501. Cited 6 times.
Document Type: Article
Publication Stage: Final
Source: Scopus

LIBRI

Familiari G, Relucenti R, Heyn R
Anatomia Microscopica. Atlante di Microscopia Ottica ed Elettronica Fondato da Pietro Motta. IV Edizione. PICCIN, Padova, pp. 879, 2017. ISBN 978-88-299-2684-8

Relucenti M, Petruzziello L, Familiari G, Heyn R
A simple and reliable method to prepare semen for transmission electron microscopy.
In: Microscopy: Science, Technology, Applications and Education. Microscopy Book Series volume 1. Edited by A. Méndez-Vilas, J. Díaz Álvarez, Formatex Research Center (FORMATEX), Spain, pp. 151-155, 2010. ISBN (13): 978-84-614-6189-9

Heyn R, Relucenti M, Petruzziello L, Franchitto G, Pastore A, Palleschi G, Carbone A, Rago R, Petrozza V, Familiari G
Ultrastruttura del testicolo in soggetto Klinefelter non associato a mosaicismo e non azoospermico.
La Riproduzione Umana. Prevenzione, Clinica e Terapia. Edited by C. Foresta, A. Lenzi, A. Ferlin, A. Grolla. Coop. Libraria Editrice Università di Padova. pp. 399-403, 2009. Joint Congress SIFR (Italian Society of Reproductive Physiopathology) and SIAMS (Italian Society of Andrology and Sexual Medicine). Abano Terme Italy, February 27-28th 2009.

Familiari G, Relucenti M, Familiari A, Battaglione E, Franchitto G, Heyn R
Visualization of the real microarchitecture of glycoprotein matrices with scanning electron microscopy. Modern Research and Educational Topics in Microscopy. Volume 1. Applications in Biology and Medicine. Edited by A. Méndez-Vilas, J. Díaz, FORMATEX; Spain, pp. 224-228, 2007. ISBN: 978-84-611-9419-3

Motta PM, Makabe S, Heyn R (collaboration)
An Atlas of Menopausal Aging (A photographic atlas of colored electron microscopy images on the menopause). The Encyclopedia of Visual Medicine Series. The Parthenon Publishing Group (London), 2003.

Heyn R, Ursu S, Motta PM
[Morphology of the adult ovary, in Italian]. In: A.R. Genazzani, A. Gadducci, M. Gambacciani, (editors). [The ovary]. Volume 1: [Organs in Gynaecology, Physiopathology, Clinics and Therapy]. CIC Edizioni Internazionali, Rome, pp. 35-49, 2003.

Firmato
Rosemari Brigitte Heyn Salinas