Catalogo dei Corsi di studio

http://dsb.uniroma1.it/dipartimento/persone

CURRICULUM VITAE

Stefano Pascarella

Full Professor
Dipartimento di Scienze biochimiche A. Rossi Fanelli Sapienza Università di Roma
Tel. +39 06 4991 7694
e-mail Stefano.Pascarella@uniroma1.it

WORK EXPERIENCE

2001-today Full Professor BIO/10; Sapienza Università di Roma; Teaching and Research activity: Biochemistry, Structural Bioinformatics

2000-2001 Associate Professor BIO/10; Sapienza Università di Roma; Teaching and Research activity: Biochemistry, Structural Bioinformatics

1991-2000 Ricercatore BIO/10; Sapienza Università di Roma; Teaching and Research activity: Biochemistry, Structural Bioinformatics

1990-1991 Post-doc fellow (European Community Fellowship; EMBO Fellowship)
EMBL Heidelberg; Biocomputing division. Research activity: Structural Bioinformatics

1989 (1 m) Visiting fellow; Department of Biochemistry, Medical College of Virginia, Richmond, Virginia, U.S.A. Research activity: Biochemistry

1985 (3 m) Visiting fellow; Department of Biochemistry, Medical College of Virginia, Richmond, Virginia, U.S.A. Research activity: Biochemistry

EDUCATION AND TRAINING

1986-1989 PhD in Biochemistry
University of Rome, La Sapienza
Project: Site directed mutagenesis of Serine hydroxymethyltransferase; protein purification; structural bioinformatics

1984 Laurea in Scienze biologiche 110/110 cum laude
University of Rome, La Sapienza
Project: Determination of the primary structure of cytosolic rabbit SHMT

1978 Maturità classica (Grammar school)
Liceo Ginnasio Statale Luciano Manara

PERSONAL SKILLS

Mother tongue Italian

Other languages UNDERSTANDING SPEAKING WRITING
Listening Reading Spoken interaction Spoken production
English B2 C1 B2 B2 C1
German A2 A2 A1 A1 A2
French A1 A1 A1 A1 A1

ORGANIZATIONAL AND TEACHING ACTIVITIES

Tutor of PhD, Graduate, and Post-Docs students
Co-founder and member of the of the Teaching Board of the one-year Master in Bioinformatics (since 2001)
Director of the Master in Bioinformatics (since 201o)
Principal investigator of research projects
Member of Department commissions
Member of the Teaching Board of the former PhD program in Biophysics (until 2013)
Member of the Teaching Board of PhD program in Biochemistry (since 2015)
Course of Biochemistry (Biological Sciences)
Course of Bioinformatics (Master in Genomics, Industrial and Environmental Biotechnology)

TECHICAL SKILLS

Molecular Graphics; Web site management; Use of software for protein and nucleic acid sequences and protein structure analysis.
Computer programming using Perl, C and bash scripting. Operating systems: Mac OS-X, Linux, MS Windows. R language.

FUNDING

Principal investigator of Sapienza University Research Projects;
Participant in National Research Projects (PRIN);
Participant in Cenci-Bolognetti projects;
Principal investigator of the PNRA (Progetto Nazionale Ricerca Antartide) 2004 1.8
Participant in Progetto FILAS 2016 Regione Lazio

OTHER ACTIVITIES

Referee for international scientific journals: AminoAcids; BBA; Bioinformatics; BMC Structural biology; Computational biology and chemistry; Current microbiology; Genome Biology and Evolution; Gene; Interdisciplinary sciences: computational life sciences; J Computer Aided Molecular Design; Microbial genomics; Molecular BioSystems; Plos ONE; Scientific Report; European Journal of Biochemistry; FEBS journal; Comparative Biochemistry and Physiology
Member of the Biotechnology panel evaluation in the framework of IV FP of the European Commission
Referee for evaluation of scientific projects (Norway, Poland);
Referee for evaluation of National Projects (PRIN)
Program Committee member of the Meetings BITS2012, BITS2013, BITS2014;
Associate Editor of the BITS Supplement to BMC Bioinformatics (2012, 2013, 2014);
Member of the Editorial Board of Biochemistry Research International, Hindawi Publishing Corporation;
Member of the Editorial Board of BioMed Research International, Hindawi Publishing
Guest Editor of Symmetry Special Issue: "Structural Symmetry and Protein Function", MDPI Publishing
Member of the Editorial Board of Open Life Sciences, De Gruyter Publishing
Sapienza delegate with the ELIXIR-IIB Board (since 2017)

INVITED ORALCONTRIBUTIONS

VI National meeting Proteine 91 , Trieste
Vitamin B6 and carbonyl catalysis , Capri, 22-27 Maggio 1994
National School in Protein Science (Urbino, 5-9 settembre 1994)
National School in Protein Scienc (Urbino, 18-22 settembre 1995)
School in Protein Structure and Function (L Aquila, 25-27 Maggio 2000)
Course Bioinformatica , IST, Genova 1-2 luglio, 2004
SIB-BIB 2000 Meeting Biochemistry and Biotechnology , Como, June 27-29, 2000
XVII National SIB Meeting Proteine 2004 , Viterbo, May 20-22, 2004
Lecture, Dipartimento di Biotecnologie e Bioscienze Università degli Studi di Milano Bicocca , Dec 15, 2004
SIB Workshop "Biologia Computazionale e di Sistema", Bologna, June 28, 2017

MEMBERSHIPS

SIB, Società Italiana di Biochimica e Biologia Molecolare
BITS, Italian Society of Bioinformatics

PUBLICATIONS

H-index = 28 (Google scholar @ June 2018)
Total number of citations = 2342 (Google scholar @ June 2018)
ResearchGate score = 35.10 (June 2018)

Milano T, Gulzar A, Narzi D, Guidoni L, Pascarella S.
Molecular dynamics simulation unveils the conformational flexibility of the interdomain linker in the bacterial transcriptional regulator GabR from Bacillus subtilis bound to pyridoxal 5'-phosphate. PLoS One. (2017) Dec 18;12(12):e0189270.

Milano T, Angelaccio S, Tramonti A, di Salvo ML, Nogues I, Contestabile R, Pascarella S.
A Comprehensive Computational Analysis of Mycobacterium Genomes Pinpoints the Genes Co-occurring with YczE, a Membrane Protein Coding Gene Under the Putative Control of a MocR, and Predicts its Function.
(2017 ) Interdiscip Sci. Nov 2. doi: 10.1007/s12539-017-0266-z.

Mugosa, B., Cella, E., Lai, A., Lo Presti, A., Blasi, A., Vratnica, Z., Vujo evic, D., Ebranati, E., Lau evic, D., Guarino, M., Zehender, G., Milano, T., Pascarella, S., Spoto, S., Angeletti, S., Ciccozzi, M.
Hepatitis C virus genotype 3A in a population of injecting drug users in Montenegro: Bayesian and evolutionary analysis
(2017) Archives of Virology, 162 (6), pp. 1549-1561.

Tramonti, A., Milano, T., Nardella, C., di Salvo, M.L., Pascarella, S., Contestabile, R.
Salmonella typhimurium PtsJ is a novel MocR-like transcriptional repressor involved in regulating the vitamin B6 salvage pathway
(2017) FEBS Journal, 284 (3), pp. 466-484.

Amidani, D., Tramonti, A., Canosa, A.V., Campanini, B., Maggi, S., Milano, T., di Salvo, M.L., Pascarella, S., Contestabile, R., Bettati, S., Rivetti, C.
Study of DNA binding and bending by Bacillus subtilis GabR, a PLP-dependent transcription factor
(2017) Biochimica et Biophysica Acta - General Subjects, 1861 (1), pp. 3474-3489.

Milano, T., Angelaccio, S., Tramonti, A., Di Salvo, M.L., Contestabile, R., Pascarella, S.
Structural properties of the linkers connecting the N- and C- terminal domains in the MocR bacterial transcriptional regulators
(2016) Biochimie Open, 3, pp. 8-18.

Angelaccio, S., Milano, T., Tramonti, A., Di Salvo, M.L., Contestabile, R., Pascarella, S.
Data from computational analysis of the peptide linkers in the MocR bacterial transcriptional regulators
(2016) Data in Brief, 9, pp. 292-313.

Angeletti, S., Presti, A.L., Cella, E., Fogolari, M., De Florio, L., Dedej, E., Blasi, A., Milano, T., Pascarella, S., Incalzi, R.A., Coppola, R., Dicuonzo, G., Ciccozzi, M.
Klebsiella pneumoniae blaKPC-3 nosocomial epidemic: Bayesian and evolutionary analysis
(2016) Infection, Genetics and Evolution, 46, pp. 85-93.

Giovanetti, M., Milano, T., Alcantara, L.C., Carcangiu, L., Cella, E., Lai, A., Lo Presti, A., Pascarella, S., Zehender, G., Angeletti, S., Ciccozzi, M.
Zika Virus spreading in South America: Evolutionary analysis of emerging neutralizing resistant Phe279Ser strains
(2016) Asian Pacific Journal of Tropical Medicine, 9 (5), pp. 445-452.

Milano, T., Angelaccio, S., Tramonti, A., Di Salvo, M.L., Contestabile, R., Pascarella, S.
A bioinformatics analysis reveals a group of MocR bacterial transcriptional regulators linked to a family of genes coding for membrane proteins
(2016) Biochemistry Research International, 2016, art. no. 4360285, .

Tramonti, A., Fiascarelli, A., Milano, T., Di Salvo, M.L., Nogués, I., Pascarella, S., Contestabile, R.
Molecular mechanism of PdxR - A transcriptional activator involved in the regulation of vitamin B6 biosynthesis in the probiotic bacterium Bacillus clausii
(2015) FEBS Journal, 282 (15), pp. 2966-2984.

Di Salvo, M.L., Nogués, I., Parroni, A., Tramonti, A., Milano, T., Pascarella, S., Contestabile, R.
On the mechanism of Escherichia coli pyridoxal kinase inhibition by pyridoxal and pyridoxal 5 -phosphate
(2015) Biochimica et Biophysica Acta - Proteins and Proteomics, 1854 (9), art. no. 39521, pp. 1160-1166.

Milano, T., Contestabile, R., Lo Presti, A., Ciccozzi, M., Pascarella, S.
The aspartate aminotransferase-like domain of Firmicutes MocR transcriptional regulators
(2015) Computational Biology and Chemistry, 58, pp. 55-61.

Milano, T., Di Salvo, M.L., Angelaccio, S., Pascarella, S.
Conserved water molecules in bacterial serine hydroxymethyltransferases
(2015) Protein Engineering, Design and Selection, 28 (10), pp. 415-426.

Facchiano, A., Angelini, C., Bosotti, R., Guffanti, A., Marabotti, A., Marangoni, R., Pascarella, S., Romano, P., Zanzoni, A., Helmer-Citterich, M.
Preface: BITS2014, the Annual Meeting of the Italian Society of Bioinformatics
(2015) BMC Bioinformatics, 16, art. no. S1, .

Prudente, S., Jungtrakoon, P., Marucci, A., Ludovico, O., Buranasupkajorn, P., Mazza, T., Hastings, T., Milano, T., Morini, E., Mercuri, L., Bailetti, D., Mendonca, C., Alberico, F., Basile, G., Romani, M., Miccinilli, E., Pizzuti, A., Carella, M., Barbetti, F., Pascarella, S., Marchetti, P., Trischitta, V., Di Paola, R., Doria, A.
Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus
(2015) American Journal of Human Genetics, 97 (1), pp. 177-185.

Angelaccio, S., Di Salvo, M.L., Parroni, A., Di Bello, A., Contestabile, R., Pascarella, S.
Structural stability of cold-adapted serine hydroxymethyltransferase, a tool for -hydroxy- -amino acid biosynthesis
(2014) Journal of Molecular Catalysis B: Enzymatic, 110, pp. 171-177.

Angelaccio, S., Dworkowski, F., Di Bello, A., Milano, T., Capitani, G., Pascarella, S.
Conformational transitions driven by pyridoxal-5 -phosphate uptake in the psychrophilic serine hydroxymethyltransferase from Psychromonas ingrahamii
(2014) Proteins: Structure, Function and Bioinformatics, 82 (10), pp. 2831-2841.

Paiardini, A., Aducci, P., Cervoni, L., Cutruzzolà, F., Di Lucente, C., Janson, G., Pascarella, S., Rinaldo, S., Visconti, S., Camoni, L.
The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets
(2014) IUBMB Life, 66 (1), pp. 52-62.

Milano, T., Paiardini, A., Grgurina, I., Pascarella, S.
Type i pyridoxal 5 -phosphate dependent enzymatic domains embedded within multimodular nonribosomal peptide synthetase and polyketide synthase assembly lines
(2013) BMC Structural Biology, 13 (1), art. no. 26, .

Paiardini, A., Pascarella, S.
Structural mimicry between SLA/LP and Rickettsia surface antigens as a driver of autoimmune hepatitis: Insights from an in silico study
(2013) Theoretical Biology and Medical Modelling, 10 (1), art. no. 25, .

Singh, R., Spyrakis, F., Cozzini, P., Paiardini, A., Pascarella, S., Mozzarelli, A.
Chemogenomics of pyridoxal 5 -phosphate dependent enzymes
(2013) Journal of Enzyme Inhibition and Medicinal Chemistry, 28 (1), pp. 183-194.

Fullone, M.R., Paiardini, A., Miele, R., Marsango, S., Gross, D.C., Omura, S., Ros-Herrera, E., Bonaccorsi Di Patti, M.C., Laganà, A., Pascarella, S., Grgurina, I.
Insight into the structure-function relationship of the nonheme iron halogenases involved in the biosynthesis of 4-chlorothreonine - Thr3 from Streptomyces sp. OH-5093 and SyrB2 from Pseudomonas syringae pv. syringae B301DR
(2012) FEBS Journal, 279 (23), pp. 4269-4282.

Bramucci, E., Paiardini, A., Bossa, F., Pascarella, S.
PyMod: Sequence similarity searches, multiple sequence-structure alignments, and homology modeling within PyMOL
(2012) BMC Bioinformatics, 13 (SUPPL.4), art. no. S2, .

Angelaccio, S., Florio, R., Consalvi, V., Festa, G., Pascarella, S.
Serine hydroxymethyltransferase from the cold adapted microorganism Psychromonas ingrahamii: A low temperature active enzyme with broad substrate specificity
(2012) International Journal of Molecular Sciences, 13 (2), pp. 1314-1326.

Siglioccolo, A., Paiardini, A., Piscitelli, M., Pascarella, S.
Structural adaptation of extreme halophilic proteins through decrease of conserved hydrophobic contact surface
(2011) BMC Structural Biology, 11, art. no. 50, .

Bramucci, E., Milano, T., Pascarella, S.
Genomic distribution and heterogeneity of MocR-like transcriptional factors containing a domain belonging to the superfamily of the pyridoxal-5'-phosphate dependent enzymes of fold type I
(2011) Biochemical and Biophysical Research Communications, 415 (1), pp. 88-93.

Siglioccolo, A., Gerace, R., Pascarella, S.
Cold spots in protein cold adaptation: Insights from normalized atomic displacement parameters (B -factors)
(2010) Biophysical Chemistry, 153 (1), pp. 104-114.

Siglioccolo, A., Bossa, F., Pascarella, S.
Structural adaptation of serine hydroxymethyltransferase to low temperatures
(2010) International Journal of Biological Macromolecules, 46 (1), pp. 37-46.

Severino, V., Paiardini, A., Pascarella, S., Parente, A., Chambery, A.
Structural analysis of toxic volkensin, a type 2 ribosome inactivating protein from Adenia volkensii Harm (kilyambiti plant): Molecular modeling and surface analysis by computational methods and limited proteolysis
(2009) International Journal of Biological Macromolecules, 45 (4), pp. 407-413.

Baldasseroni, F., Pascarella, S.
Subunit interfaces of oligomeric hyperthermophilic enzymes display enhanced compactness
(2009) International Journal of Biological Macromolecules, 44 (4), pp. 353-360.

Maugini, E., Tronelli, D., Bossa, F., Pascarella, S.
Structural adaptation of the subunit interface of oligomeric thermophilic and hyperthermophilic enzymes
(2009) Computational Biology and Chemistry, 33 (2), pp. 137-148.

Paiardini, A., Sali, R., Bossa, F., Pascarella, S.
"Hot cores" in proteins: Comparative analysis of the apolar contact area in structures from hyper/thermophilic and mesophilic organisms
(2008) BMC Structural Biology, 8, art. no. 14, .

Tronelli, D., Maugini, E., Bossa, F., Pascarella, S.
Structural adaptation to low temperatures - Analysis of the subunit interface of oligomeric psychrophilic enzymes
(2007) FEBS Journal, 274 (17), pp. 4595-4608.

Gianese, G., Pascarella, S.
A consensus procedure improving solvent accessibility prediction
(2006) Journal of Computational Chemistry, 27 (5), pp. 621-626.

Paiardini, A., Bossa, F., Pascarella, S.
CAMPO, SCR_FIND and CHC_FIND: A suite of web tools for computational structural biology
(2005) Nucleic Acids Research, 33 (SUPPL. 2), pp. W50-W55.

Di Vincenzo, L., Grgurina, I., Pascarella, S.
In silico analysis of the adenylation domains of the freestanding enzymes belonging to the eucaryotic nonribosomal peptide synthetase-like family
(2005) FEBS Journal, 272 (4), pp. 929-941.

Paiardini, A., Bossa, F., Pascarella, S.
Evolutionarily conserved regions and hydrophobic contacts at the superfamily level: The case of the fold-type I, pyridoxal-5 -phosphate- dependent enzymes
(2004) Protein Science, 13 (11), pp. 2992-3005.

Brisdelli, F., Saliola, M., Pascarella, S., Luzi, C., Franceschini, N., Falcone, C., Martini, F., Bozzi, A.
Kinetic properties of native and mutagenized isoforms of mitochondrial alcohol dehydrogenase III purified from Kluyveromyces lactis
(2004) Biochimie, 86 (9-10), pp. 705-712.

Gianese, G., Bossa, F., Pascarella, S.
Improvement in prediction of solvent accessibility by probability profiles
(2003) Protein Engineering, 16 (12), pp. 987-992.

Paiardini, A., Contestabile, R., D'Aguanno, S., Pascarella, S., Bossa, F.
Threonine aldolase and alanine racemase: Novel examples of convergent evolution in the superfamily of vitamin B6-dependent enzymes
(2003) Biochimica et Biophysica Acta - Proteins and Proteomics, 1647 (1-2), pp. 214-219.

Paiardini, A., Gianese, G., Bossa, F., Pascarella, S.
Structural plasticity of thermophilic serine hydroxymethyltransferases
(2003) Proteins: Structure, Function and Genetics, 50 (1), pp. 122-134.

Gianese, G., Bossa, F., Pascarella, S.
Comparative structural analysis of psychrophilic and meso- and thermophilic enzymes
(2002) Proteins: Structure, Function and Genetics, 47 (2), pp. 236-249.

Contestabile, R., Paiardini, A., Pascarella, S., Di Salvo, M.L., D'Aguanno, S., Bossa, F.
L-Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase: A subgroup of strictly related enzymes specialized for different functions
(2001) European Journal of Biochemistry, 268 (24), pp. 6508-6525.

Gianese, G., Argos, P., Pascarella, S.
Structural adaptation of enzymes to low temperatures
(2001) Protein Engineering, 14 (3), pp. 141-148.

Erba, F., Fiorucci, L., Pascarella, S., Menegatti, E., Ascenzi, P., Ascoli, F.
Selective inhibition of human mast cell tryptase by gabexate mesylate, an antiproteinase drug
(2001) Biochemical Pharmacology, 61 (3), pp. 271-276.

Ruoppolo, M., Amoresano, A., Pucci, P., Pascarella, S., Polticelli, F., Trovato, M., Menegatti, E., Ascenzi, P.
Characterization of five new low-molecular-mass trypsin inhibitors from white mustard (Sinapis alba L.) seed
(2000) European Journal of Biochemistry, 267 (21), pp. 6486-6492.

Birolo, L., Tutino, L.M., Fontanella, B., Gerday, C., Mainolfi, K., Pascarella, S., Sannia, G., Vinci, F., Marino, G.
Aspartate aminotransferase from the Antarctic bacterium Pseudoalteromonas haloplanktis TAC 125. Cloning, expression, properties, and molecular modelling
(2000) European Journal of Biochemistry, 267 (9), pp. 2790-2802.

Zamparelli, C., Ilari, A., Verzili, D., Giangiacomo, L., Colotti, G., Pascarella, S., Chiancone, E.
Structure-function relationships in sorcin, a member of the penta EF- hand family. Interaction of sorcin fragments with the ryanodine receptor and an Escherichia coli model system
(2000) Biochemistry, 39 (4), pp. 658-666.

Bonaccorsi Di Patti, M.C., Pascarella, S., Catalucci, D., Calabrese, L.
Homology modeling of the multicopper oxidase Fet3 gives new insights in the mechanism of iron transport in yeast
(1999) Protein Engineering, 12 (11), pp. 895-897.

Polticelli, F., Pascarella, S., Bordo, D., Bolognesi, M., Ascenzi, P.
The T-Knot motif revisited
(1999) Biological Chemistry, 380 (10), pp. 1247-1250.

Ascenzi, P., Ruoppolo, M., Amoresano, A., Pucci, P., Consonni, R., Zetta, L., Pascarella, S., Bortolotti, F., Menegatti, E.
Characterization of low-molecular-mass trypsin isoinhibitors from oil- rape (Brassica napus var. oleifera) seed
(1999) European Journal of Biochemistry, 261 (1), pp. 275-284.

Ascenzi, P., Bolognesi, M., Catalucci, D., Pascarella, S., Ruoppolo, M., Rizzi, M.
Leech antihemostatic proteins share the T-knot scaffold, a disulfide-reinforced structural motif
(1998) Biological Chemistry, 379 (11), pp. 1387-1389.

Pascarella, S., Angelaccio, S., Contestabile, R., Delle Fratte, S., Di Salvo, M., Bossa, F.
The structure of serine hydroxymethyltransferase as modeled by homology and validated by site-directed mutagenesis
(1998) Protein Science, 7 (9), pp. 1976-1982.

Pascarella, S., De Persio, R., Bossa, F., Argos, P.
Easy method to predict solvent accessibility from multiple protein sequence alignments
(1998) Proteins: Structure, Function and Genetics, 32 (2), pp. 190-199.

Rossi, R., Barra, D., Bellelli, A., Boumis, G., Canofeni, S., Di Simplicio, P., Lusini, L., Pascarella, S., Amiconi, G.
Fast-reacting thiols in rat hemoglobins can intercept damaging species in erythrocytes more efficiently than glutathione
(1998) Journal of Biological Chemistry, 273 (30), pp. 19198-19206.

Arnone, M.I., Birolo, L., Pascarella, S., Cubellis, M.V., Bossa, F., Sannia, G., Marino, G.
Stability of aspartate aminotransferase from Sulfolobus solfataricus
(1997) Protein Engineering, 10 (3), pp. 237-248.

Pascarella, S., Milpetz, F., Argos, P.
A databank (3D_ali) collecting related protein sequences and structures
(1996) Protein Engineering, 9 (3), pp. 249-251.

Mignogna, G., Pascarella, S., Wechselberger, C., Hinterleitner, C., Mollay, C., Amiconi, G., Barra, D., Kreil, G.
BSTI, a trypsin inhibitor from skin secretions of Bombina bombina related to protease inhibitors of nematodes
(1996) Protein Science, 5 (2), pp. 357-362.

Toney, M.D., Pascarella, S., De Biase, D.
Active site model for aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities
(1995) Protein Science, 4 (11), pp. 2366-2374.

Pascarella, S., Argos, P.
Conservation of amphipathic conformations in multiple protein structural alignments
(1994) Protein Engineering, Design and Selection, 7 (2), pp. 185-193.

Pascarella, S., Bossa, F.
Similarity between pyridoxal/pyridoxamine phosphate dependent enzymes involved in dideoxy and deoxyaminosugar biosynthesis and other pyridoxal phosphate enzymes
(1994) Protein Science, 3 (4), pp. 701-705.

Levin, J.M., Pascarella, S., Argos, P., Garnier, J.
Quantification of secondary structure prediction improvement using multiple alignments
(1993) Protein Engineering, Design and Selection, 6 (8), pp. 849-854.

Pascarella, S., Schirch, V., Bossa, F.
Similarity between serine hydroxymethyltransferase and other pyridoxal phosphate-dependent enzymes
(1993) FEBS Letters, 331 (1-2), pp. 145-149.

Pascarella, S., Argos, P.
Analysis of insertions/deletions in protein structures
(1992) Journal of Molecular Biology, 224 (2), pp. 461-471.

Pascarella, S., Argos, P.
A data bank merging related protein structures and sequences
(1992) Protein Engineering, Design and Selection, 5 (2), pp. 121-137.

Angelaccio, S., Pascarella, S., Fattori, E., Bossa, F., Strong, W., Schirch, V.
Serine Hydroxymethyltransferase: Origin of Substrate Specificity
(1992) Biochemistry, 31 (1), pp. 155-162.

Fattori, E., Angelaccio, S., Pascarella, S., Bossa, F., Barra, D., Schirch, V., Brunori, C.M.
Site-Directed Mutagenesis in the Study of Serine Hydroxy methyltransf erase [Mutagenesi sito-specifica nello studio delta serina idrossimetiltrasferasi]
(1990) Rendiconti Lincei, 1 (2), pp. 229-234.

Pascarella, S., Bossa, F.
Pronet: A microcomputer program for predicting the secondary structure of proteins with a neural network
(1989) Bioinformatics, 5 (4), pp. 319-320.

Pascarella, S., Bossa, F.
Cleavage: A microcomputer program for predicting signal sequence cleavage sites
(1989) Bioinformatics, 5 (1), pp. 53-54.

Martini, F., Maras, B., Tanci, P., Angelaccio, S., Pascarella, S., Barra, D., Bossa, F., Schirch, V.
The primary structure of rabbit liver mitochondrial serine hydroxymethyltransferase
(1989) Journal of Biological Chemistry, 264 (15), pp. 8509-8519.

Pascarella, S., Bossa, F.
Methods for identifying antigen determinants of proteins on the basis of primary structure
(1988) Italian Journal of Biochemistry, 37 (4), pp. 226a-228a.

Pascarella, S., Bossa, F.
PROTEUS: A suite of programs for prediction of structural features of proteins using an apple lie
(1987) Bioinformatics, 3 (4), pp. 325-331.

Martini, F., Angelaccio, S., Pascarella, S., Barra, D., Bossa, F., Schirch, V.
The primary structure of rabbit liver cytosolic serine hydroxymethyltransferase.
(1987) Journal of Biological Chemistry, 262 (12), pp. 5499-5509.

Pascarella, S., Bossa, F.
A simple microcomputer program for predicting the secondary structure of proteins
(1987) Computer Methods and Programs in Biomedicine, 24 (3), pp. 207-208.

Doonan, S., Martini, F., Angelaccio, S., Pascarella, S., Barra, D., Bossa, F.
The complete amino acid sequences of cytosolic and mitochondrial aspartate aminotransferases from horse heart, and inferences on evolution of the isoenzymes
(1986) Journal of Molecular Evolution, 23 (4), pp. 328-335.

Martini, F., Angelaccio, S., Barra, D., Pascarella, S., Maras, B., Doonan, S., Bossa, F.
The primary structure of mitochondrial aspartate aminotransferase from human heart
(1985) Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular, 832 (1), pp. 46-51.

TEXTBOOKS

PASCARELLA S; PAIARDINI A
(2010) Bioinformatica: dalla sequenza alla struttura delle proteine
Zanichelli BOLOGNA