Catalogo dei Corsi di studio

Stefania Mardente
Department of Experimental Medicine, Viale Regina Elena, 324- 00161 Rome Italy
(0039) 06 49970662
Stefania.Mardente@uniroma1.it
ACTUAL POSITION
University Researcher; University Lecturer; Immunopathologist
University Lecturer in Pathology and Immunology, Faculty of Medicine, Sapienza University of Rome
Senior Researcher in Pathology and Immunology, Faculty of Medicine, Sapienza University of
Senior Medical Officer, Autoimmunity Laboratory, Policlinico Umberto I, Rome
President, Degree Course in Nursing, Sapienza University of Rome
EDUCATION
Degree in Medicine (First Class Honours), Sapienza University of Rome
Award for best graduate thesis in pasteurian disciplines Cenci-Bolognetti Foundation
Italian Professional Practice Certificate in Medicine (MD)
MSc in General Pathology, Sapienza University of Rome
MSc in Immune and Allergic Diseases, Sapienza University of Rome
Research interests
My current research interest is the relationship between HMGB1, released in the tumor microenvironment,
in experimental models of thyroid cancer and neuroblastoma.
I am also interested in the biocompatibility of graphene oxide in various cell lines and three-dimensional models
(spheroids) and its possible use as a drug-carrier and carrier of intracellular messages (gene-silencing and gene over-expression).
Research positions
Post-doctoral researcher, Department of Thrombosis, Temple University, Philadelphia
(supervisor - Dr. A. Schmaier);
Post-doctoral researcher, Department of Pathology, Temple University, Philadelphia
(supervisor - Dr. B. Calabretta);
Visiting Researcher, CRC Research Group, Department of of Pathology, University of Cambridge (supervisor - Dr. B.Ponder)
Technical Supervisor and Medical Assistant, Sapienza University of Rome, Department of Experimental Medicine, Immunopathology Service
Senior Researcher in Pathology and Immunology, Faculty of Medicine, Sapienza University of Rome
University Lecturer in Pathology and Immunology, Faculty of Medicine, Sapienza University of Rome
Research projects and grants last 6 years
A loop involving miR-221, miR-222, SIRT1 and HMGB1 regulates thyroid carcinoma growth and invasion
(Sapienza University of Rome grant n. 2012106)
Biocompatibility of graphene and zinc based nanomaterials in human cell models (Bilateral research project with Moscow State University)
Hypoxia-like effect of zinc oxide nanoparticles on tumor and non-tumor cells (grant n.1550837)
Use of green functionalized graphene oxide as a message carrier into neuroblastoma/glioblastoma cell lines and into
three dimensional in vitro models (Sapienza University of Rome)
Prevention of HMGB1-mediated tumor progression by aspirin (Sapienza University of Rome)
Zinc oxide nanoparticles to convey biological macromolecules in mammalian cells: cytotoxic action and induction of autophagy
(Sapienza University of Rome)
HMGB1-induced miRNA signature in exosomes purified from thyroid cancer cell lines regulates EMT and stemness"
(Sapienza University of Rome)
Peer reviewer for the following journals:
Cellular Physiology and Biochemistry; Endocrine related cancer; ILMS, Internationl Journal of Nanomedicine; Journal of Molec Endoc ; Cancer Biomarkers; Febs letters; Plos One; International Journal of Endocrinology; OncoTargets; Biochimie; Research reports in Clinical Cardiology
Peer reviewer of research projects: Italian Research Projects of National Interest (PRIN 2016, PRIN 2019-21)
Topic editor of Applied Sciences (MDPI)
Member of the Editorial Board of Case Reports in Clinical Pathology; JSM Thyroid Disorders & Management
Senior Medical Officer, Policlinico Umberto I, Rome; (DAI Medicina diagnostica e radiologia
Scopus: Metrics overview 30-9-2022
Documents by author 28
Citations by 878 documents: 912
h-index: 12