Corso di laurea: Bioinformatica A.A. 2017/2018

Obiettivi formativi e sbocchi professionali Regolamento didattico del corso Programmazione

Primo anno

Primo semestre

Insegnamento	CFU	SSD	Ore Lezione	Ore Eserc.	Ore Lab	Ore Studio	Attività	Lingua
1049371 - PRINCIPLES OF MATHEMATICS (obiettivi) The aim of this course is to give the student sound mathematical basis in calculus of one or several variables, optimization and elementary graph theory in a way appropriate for a student bioinformatics. An emphasis will be given to applications and intuitive understanding of the underlying concepts.
- PRINCIPLES OF MATHEMATICS 2	Erogato in altro semestre o anno
- PRINCIPLES OF MATHEMATICS 1 (obiettivi) The aim of this course is to give the student sound mathematical basis in calculus of one or several variables, optimization and elementary graph theory in a way appropriate for a student bioinformatics. An emphasis will be given to applications and intuitive understanding of the underlying concepts.	6	MAT/09	24	36	-	-	Attività formative di base	ENG
1049372 - ORGANIC AND INORGANIC CHEMISTRY (obiettivi) This course is an introduction to chemistry fundamentals addressed to students with limited chemistry background. The purpose of the course is to provide students with the knowledge of general chemistry principles, and with the tools to solve simple chemistry problems. At the end of the course the students are expected to know ho to apply the acquired chemical concepts to different fields, including pharmaceutical chemistry and biochemistry which are the subjects of further courses. The course aims to provide a correct knowledge of the fundamental principles of organic chemistry, proposing the contents into two distinct phases that are closely and logically linked. In the first phase the teaching is addressed to provide basic knowledge about classification and nomenclature of organic compounds, about the symbolism used to represent both structures and reactions, as well as over the chemical-physics, acid-base, nucleophilic-electrophilic properties of the considered compounds. In the second phase the teaching is instead focused on the description of the different reactivity involved by different classes of compounds, rationalizing the study through the analysis of the relevant mechanisms. In the context of the described methodology the objectives to be achieved are: 1) attainment of a suitable degree of specialized knowledge, understood as the ability to invoke theories, rules, nomenclature etc.; 2) capacity to properly interpret and process the reaction schemes and propose alternatives to the encountered syntheses; 3) establish connections between different studied subjects.
- ORGANIC AND INORGANIC CHEMISTRY 2	Erogato in altro semestre o anno
- ORGANIC AND INORGANIC CHEMISTRY 1 (obiettivi) This course is an introduction to chemistry fundamentals addressed to students with limited chemistry background. The purpose of the course is to provide students with the knowledge of general chemistry principles, and with the tools to solve simple chemistry problems. At the end of the course the students are expected to know ho to apply the acquired chemical concepts to different fields, including pharmaceutical chemistry and biochemistry which are the subjects of further courses.	6	CHIM/03	48	-	-	-	Attività formative di base	ENG
1049251 - PRINCIPLES OF PHYSICS (obiettivi) The Physics course has several distinct aims. First, it aims to full the gap between school and university level physics. Second, it aims to provide a much logical and analytical framework for classical physics, which will be essential for the course. Third, it includes bio-medical themes generally underestimated in basic physics courses. Such topics will be selected among those that will be developed in the subsequent years of the course. Fourth, single lectures aim to broaden the student’s perspectives, so that he can begin to appreciate the great flexibility and generality of the laws of physics and their application in emerging biomedical fields of research.	6	FIS/07	48	-	-	-	Attività formative di base	ENG
1049253 - PRINCIPLES OF COMPUTER SCIENCE I (obiettivi) The goal of this course is to empower students with those basic programming skills needed to deal with bioinformatics data. More specifically, at the end of the course the students will be able to: - model problems of medium difficulty and solve them by programming; - decompose complex programming problems into simpler problems; - implement well-designed and well-coded software - test and debug programs - analyse programs with respect to their correctness and efficiency - use Python and its libraries These skills are essential in order to analyse bioinformatics data using software libraries and scripts	6	INF/01	48	-	-	-	Attività formative di base	ENG
1049373 - BIOLOGY OF THE CELL (obiettivi) Students acquire the knowledge and thinking skills necessary to understand biological problems in a evolutionary perspective. The course will provide students with understanding of the basic molecular mechanisms that operate in living cells, with a focus on the flow of genetic information.
- BIOLOGY OF THE CELL 2	Erogato in altro semestre o anno
- BIOLOGY OF THE CELL 1 (obiettivi) Students acquire the knowledge and thinking skills necessary to understand biological problems in a evolutionary perspective. The course will provide students with understanding of the basic molecular mechanisms that operate in living cells, with a focus on the flow of genetic information.	6	BIO/13	32	-	12	-	Attività formative caratterizzanti	ENG

Secondo semestre

Insegnamento	CFU	SSD	Ore Lezione	Ore Eserc.	Ore Lab	Ore Studio	Attività	Lingua
1049371 - PRINCIPLES OF MATHEMATICS (obiettivi) The aim of this course is to give the student sound mathematical basis in calculus of one or several variables, optimization and elementary graph theory in a way appropriate for a student bioinformatics. An emphasis will be given to applications and intuitive understanding of the underlying concepts.
- PRINCIPLES OF MATHEMATICS 2 (obiettivi) The aim of this course is to give the student sound mathematical basis in calculus of one or several variables, optimization and elementary graph theory in a way appropriate for a student bioinformatics. An emphasis will be given to applications and intuitive understanding of the underlying concepts.	6	MAT/09	48	-	-	-	Attività formative di base	ENG
- PRINCIPLES OF MATHEMATICS 1	Erogato in altro semestre o anno
1049372 - ORGANIC AND INORGANIC CHEMISTRY (obiettivi) This course is an introduction to chemistry fundamentals addressed to students with limited chemistry background. The purpose of the course is to provide students with the knowledge of general chemistry principles, and with the tools to solve simple chemistry problems. At the end of the course the students are expected to know ho to apply the acquired chemical concepts to different fields, including pharmaceutical chemistry and biochemistry which are the subjects of further courses. The course aims to provide a correct knowledge of the fundamental principles of organic chemistry, proposing the contents into two distinct phases that are closely and logically linked. In the first phase the teaching is addressed to provide basic knowledge about classification and nomenclature of organic compounds, about the symbolism used to represent both structures and reactions, as well as over the chemical-physics, acid-base, nucleophilic-electrophilic properties of the considered compounds. In the second phase the teaching is instead focused on the description of the different reactivity involved by different classes of compounds, rationalizing the study through the analysis of the relevant mechanisms. In the context of the described methodology the objectives to be achieved are: 1) attainment of a suitable degree of specialized knowledge, understood as the ability to invoke theories, rules, nomenclature etc.; 2) capacity to properly interpret and process the reaction schemes and propose alternatives to the encountered syntheses; 3) establish connections between different studied subjects.
- ORGANIC AND INORGANIC CHEMISTRY 2 (obiettivi) The course aims to provide a correct knowledge of the fundamental principles of organic chemistry, proposing the contents into two distinct phases that are closely and logically linked. In the first phase the teaching is addressed to provide basic knowledge about classification and nomenclature of organic compounds, about the symbolism used to represent both structures and reactions, as well as over the chemical-physics, acid-base, nucleophilic-electrophilic properties of the considered compounds. In the second phase the teaching is instead focused on the description of the different reactivity involved by different classes of compounds, rationalizing the study through the analysis of the relevant mechanisms. In the context of the described methodology the objectives to be achieved are: 1) attainment of a suitable degree of specialized knowledge, understood as the ability to invoke theories, rules, nomenclature etc.; 2) capacity to properly interpret and process the reaction schemes and propose alternatives to the encountered syntheses; 3) establish connections between different studied subjects.	6	CHIM/06	48	-	-	-	Attività formative di base	ENG
- ORGANIC AND INORGANIC CHEMISTRY 1	Erogato in altro semestre o anno
1049376 - INTRODUCTION TO BIOMEDICAL STATISTICS (obiettivi) This course provides an introduction to basic concepts of Statistics and Probability for students in the biosciences.
- INTRODUCTION TO BIOMEDICAL STATISTICS 1 (obiettivi) This course provides an introduction to basic concepts of Statistics and Probability for students in the biosciences.	6	SECS-S/01	48	-	-	-	Attività formative di base	ITA
- INTRODUCTION TO BIOMEDICAL STATISTICS 2	6	MED/01	48	-	-	-	Attività formative di base	ITA
1049373 - BIOLOGY OF THE CELL (obiettivi) Students acquire the knowledge and thinking skills necessary to understand biological problems in a evolutionary perspective. The course will provide students with understanding of the basic molecular mechanisms that operate in living cells, with a focus on the flow of genetic information.
- BIOLOGY OF THE CELL 2 (obiettivi) Students acquire the knowledge and thinking skills necessary to understand biological problems in a evolutionary perspective. The course will provide students with understanding of the basic molecular mechanisms that operate in living cells, with a focus on the flow of genetic information.	6	BIO/13	48	-	-	-	Attività formative caratterizzanti	ENG
- BIOLOGY OF THE CELL 1	Erogato in altro semestre o anno

Secondo anno

Primo semestre

Insegnamento	CFU	SSD	Ore Lezione	Ore Eserc.	Ore Lab	Ore Studio	Attività	Lingua
1052115 - GENETICS AND COMPUTATIONAL GENOMICS (obiettivi) The purpose of the course is to provide students with a deep understanding of the theoretical and practical tools to solve genetic problems. Fundamentals concepts in genetics, functioning and evolution will be reconsidered in light of the sequencing and re-sequencing projects. Computational genetics has been an important area of science since the discovery of the first sequencing method and advances in tools and techniques for data generation are rapidly increasing the amount of data available to researchers. During the course, students will learn to rely on computational and data science tools for the storage, management, analysis, and visualization of genetic data.	6	BIO/18	48	-	-	-	Attività formative caratterizzanti	ENG
1049261 - PRINCIPLES OF COMPUTER SCIENCE II (obiettivi) The course aim to introduce the algorithmic approach to solving problems correctly and efficiently. Algorithms are ubiquitous in bioinformatics and are often at the interface of computer science and biology. Well established algorithmic techniques will be studied as well as ways to encode them in a computer programme using python.	6	ING-INF/05	48	-	-	-	Attività formative affini ed integrative	ENG
1049256 - MICROBIOLOGY (obiettivi) To introduce the microbial diversity, the structure/function relationship of prokaryotic cells and viruses, the microbial taxonomy and the basic principles of clinical, environmental and industrial microbiology.	6	BIO/19	40	-	12	-	Attività formative caratterizzanti	ENG
1049375 - MOLECULAR BIOLOGY (obiettivi) Main goal of the course is to give to the students a general view of the molecular mechanisms which are at the base of the biological processes. For each argument a methodological section will introduce the students to the main technical approaches used at the state of the art. Practical training (2 CFU) will make the students to breath the atmosphere of a molecular biology laboratory. Particular attention will be given to the high throughput methods utilized in “Omic” approaches to the comprehension of biological processes which will be further illustrated in the course of Molecular Biology and Genomics.
- MOLECULAR BIOLOGY 2	Erogato in altro semestre o anno
- MOLECULAR BIOLOGY 1 (obiettivi) Main goal of the course is to give to the students a general view of the molecular mechanisms which are at the base of the biological processes. For each argument a methodological section will introduce the students to the main technical approaches used at the state of the art. Practical training (2 CFU) will make the students to breath the atmosphere of a molecular biology laboratory. Particular attention will be given to the high throughput methods utilized in “Omic” approaches to the comprehension of biological processes which will be further illustrated in the course of Molecular Biology and Genomics.	6	BIO/11	48	-	-	-	Attività formative di base	ENG
1049377 - BIOCHEMISTRY (obiettivi) KNOWLEDGE AND UNDERSTANDING The main goal of the module is to provide students with the necessary tools for a detailed analysis of the structure of proteins and their macromolecular complexes. The first part of the module is dedicated to the understanding of the physico-chemical properties of the amino acids and their interaction within a protein. During the second part of the module, students are challenged with practical sessions on the structural analysis of protein models, also by means of open source software. The module consists of lectures that cover the main topics of the program and practical exercises. Exercises are carried out in a computer room with the use of open source software for the visualization of the tridimensional structure of macromolecules. Beside textbooks, students have access to lectures' slides, scientific articles, and other teaching resources made available trough this web site. APPLYING KNOWLEDGE AND UNDERSTANDING The educational objective of the module is to achieve the necessary knowledge for a critical analysis of the structure of proteins and their interactors. By the end of the module students will have acquired the skills necessary to deal with the analysis and experimental study of biological macromolecules. They will learn how to retrieve the coordinates of macromolecules from the PDB database, recognize the fold and use software for a detailed analysis of their structure. MAKING JUDGEMENTS The module is aimed at increasing the ability to critically analyze the structure of proteins and other macromolecules. COMMUNICATION SKILLS The module includes significant activity of classroom discussion aimed at developing the ability of students to transfer skills acquired in support of their arguments. In the final exam, students must take an oral presentation on the structure and function of an assigned protein. LEARNING SKILLS The many advancements of scientific research, particularly in the field of biochemistry and molecular biology, require a constant updating. For this reason, the module aims to provide the necessary tools to achieve a wider knowledge and to align skills to the advancement in biology and bioinformatics research. Biochemistry 2 – (6 cfu) This module provides an overview of the basic principles of metabolism with emphasis on the structural and regulative aspects. The course will be supported by practical sessions in the computer room available at the Department of Biochemical sciences.
- BIOCHEMISTRY 2	Erogato in altro semestre o anno
- BIOCHEMISTRY 1 (obiettivi) KNOWLEDGE AND UNDERSTANDING The main goal of the module is to provide students with the necessary tools for a detailed analysis of the structure of proteins and their macromolecular complexes. The first part of the module is dedicated to the understanding of the physico-chemical properties of the amino acids and their interaction within a protein. During the second part of the module, students are challenged with practical sessions on the structural analysis of protein models, also by means of open source software. The module consists of lectures that cover the main topics of the program and practical exercises. Exercises are carried out in a computer room with the use of open source software for the visualization of the tridimensional structure of macromolecules. Beside textbooks, students have access to lectures' slides, scientific articles, and other teaching resources made available trough this web site. APPLYING KNOWLEDGE AND UNDERSTANDING The educational objective of the module is to achieve the necessary knowledge for a critical analysis of the structure of proteins and their interactors. By the end of the module students will have acquired the skills necessary to deal with the analysis and experimental study of biological macromolecules. They will learn how to retrieve the coordinates of macromolecules from the PDB database, recognize the fold and use software for a detailed analysis of their structure. MAKING JUDGEMENTS The module is aimed at increasing the ability to critically analyze the structure of proteins and other macromolecules. COMMUNICATION SKILLS The module includes significant activity of classroom discussion aimed at developing the ability of students to transfer skills acquired in support of their arguments. In the final exam, students must take an oral presentation on the structure and function of an assigned protein. LEARNING SKILLS The many advancements of scientific research, particularly in the field of biochemistry and molecular biology, require a constant updating. For this reason, the module aims to provide the necessary tools to achieve a wider knowledge and to align skills to the advancement in biology and bioinformatics research.	6	BIO/10	40	12	-	-	Attività formative caratterizzanti	ENG

Secondo semestre

Insegnamento	CFU	SSD	Ore Lezione	Ore Eserc.	Ore Lab	Ore Studio	Attività	Lingua
1049260 - IMMUNOLOGY AND MOLECULAR PATHOLOGIES	6	MED/04	48	-	-	-	Attività formative caratterizzanti	ENG
1049375 - MOLECULAR BIOLOGY (obiettivi) Main goal of the course is to give to the students a general view of the molecular mechanisms which are at the base of the biological processes. For each argument a methodological section will introduce the students to the main technical approaches used at the state of the art. Practical training (2 CFU) will make the students to breath the atmosphere of a molecular biology laboratory. Particular attention will be given to the high throughput methods utilized in “Omic” approaches to the comprehension of biological processes which will be further illustrated in the course of Molecular Biology and Genomics.
- MOLECULAR BIOLOGY 2 (obiettivi) Main goal of the course is to give to the students a general view of the molecular mechanisms which are at the base of the biological processes. For each argument a methodological section will introduce the students to the main technical approaches used at the state of the art. Practical training (2 CFU) will make the students to breath the atmosphere of a molecular biology laboratory. Particular attention will be given to the high throughput methods utilized in “Omic” approaches to the comprehension of biological processes which will be further illustrated in the course of Molecular Biology and Genomics.	6	BIO/11	32	-	24	-	Attività formative di base	ENG
- MOLECULAR BIOLOGY 1	Erogato in altro semestre o anno
1049377 - BIOCHEMISTRY (obiettivi) KNOWLEDGE AND UNDERSTANDING The main goal of the module is to provide students with the necessary tools for a detailed analysis of the structure of proteins and their macromolecular complexes. The first part of the module is dedicated to the understanding of the physico-chemical properties of the amino acids and their interaction within a protein. During the second part of the module, students are challenged with practical sessions on the structural analysis of protein models, also by means of open source software. The module consists of lectures that cover the main topics of the program and practical exercises. Exercises are carried out in a computer room with the use of open source software for the visualization of the tridimensional structure of macromolecules. Beside textbooks, students have access to lectures' slides, scientific articles, and other teaching resources made available trough this web site. APPLYING KNOWLEDGE AND UNDERSTANDING The educational objective of the module is to achieve the necessary knowledge for a critical analysis of the structure of proteins and their interactors. By the end of the module students will have acquired the skills necessary to deal with the analysis and experimental study of biological macromolecules. They will learn how to retrieve the coordinates of macromolecules from the PDB database, recognize the fold and use software for a detailed analysis of their structure. MAKING JUDGEMENTS The module is aimed at increasing the ability to critically analyze the structure of proteins and other macromolecules. COMMUNICATION SKILLS The module includes significant activity of classroom discussion aimed at developing the ability of students to transfer skills acquired in support of their arguments. In the final exam, students must take an oral presentation on the structure and function of an assigned protein. LEARNING SKILLS The many advancements of scientific research, particularly in the field of biochemistry and molecular biology, require a constant updating. For this reason, the module aims to provide the necessary tools to achieve a wider knowledge and to align skills to the advancement in biology and bioinformatics research. Biochemistry 2 – (6 cfu) This module provides an overview of the basic principles of metabolism with emphasis on the structural and regulative aspects. The course will be supported by practical sessions in the computer room available at the Department of Biochemical sciences.
- BIOCHEMISTRY 2 (obiettivi) OBJECTIVES The aim of the Course of Biochemistry II is to provide the basic knowledge in the fundamental areas of biochemistry, namely the structural organization of proteins and their most important functions in the transport of molecules and enzymic catalysis, as well as the overview of the main metabolic pathways and their role in the global metabolism of living organisms. In particular, the students will be encouraged to apply the acquired knowledge to new problems and to appreciate how their understanding of biochemistry can contribute to solving problems in medicine, agricultural and environmental sciences. The topics illustrated in the formal lectures will be complemented by exercises and examples on the relevance of the metabolic changes for human health, with the aim to stimulate the participation of the students in a problem-solving approach and to facilitate the learning of the illustrated topics. ACQUIRED KNOWLEDGE The students will gain an understanding on the functions of cells at a molecular level. The study of the main the metabolic pathways will provide, on one hand, an insight into various types of catalytic mechanisms and, on the other hand, the overview of the anabolic and catabolic pathways operating in a living cell, as well as on the mechanisms of allosteric and hormonal regulation of the enzyme activity, signal transduction pathways and the interdependence and connectivity between the metabolic pathways. ACQUIRED COMPETENCES The students will be able to use the acquired knowledge to tackle new problems that are at the frontier of modern research regarding the metabolism, ranging from enzyme inhibition as a tool in pharmaceutical research to the possible effects of genetic mutations on distantly related biological processes. They will be able to envisage how the metabolic network responds to biological stimuli and environmental conditions. In particular, the metabolomic research can allow the identification of disease biomarkers and the knowledge of the metabolic pathways can help to identify the origin of a metabolic disorder.	6	BIO/10	40	-	12	-	Attività formative caratterizzanti	ENG
- BIOCHEMISTRY 1	Erogato in altro semestre o anno
1055572 - BIOINFORMATICS I	6	INF/01	48	-	-	-	Attività formative affini ed integrative	ENG
1049264 - PHARMACEUTICAL CHEMISTRY (obiettivi) During the course the student will learn the basics to design a drug through computational methods. The aim of the course is to impart an understanding of what medicinal chemists consider when attempting to design new pharmaceuticals. The course is twofold: a theoretical part and practical section. In the first part the course will describe the principles involved in modern drug design and drug discovery, usually with reference to compounds in current clinical usage. In the second part practical sections will be set up to teach the student some computational methods to apply in the drug design process.	6	CHIM/08	32	40	-	-	Attività formative caratterizzanti	ENG

Terzo anno

Primo semestre

Insegnamento

CFU

SSD

Ore Lezione

Ore Eserc.

Ore Lab

Ore Studio

Attività

Lingua

1049266 - BIOINFORMATICS II (obiettivi)

ING-INF/06

Attività formative affini ed integrative

ENG

1049265 - BIOETHICS (obiettivi)

MED/02

Attività formative caratterizzanti

ENG

1049258 - MOLECULAR BIOLOGY AND GENOMICS (obiettivi)

BIO/11

Attività formative caratterizzanti

ENG

Gruppo opzionale: Gruppo OPZIONALE - (visualizza)

1049267 - MODELLING AND SIMULATION OF BIOMOLECULAR DYNAMICAL SYSTEMS (obiettivi) This course aims to provide students with a practical and hands-on experience with common modeling and simulation tools in molecular biology. It would be expected that after completing this course a student would be able to model and simulate using Matlab a biomolecular systems like, for example, a gene regulatory network using the appropriate methodology. Further, students will understand the basic theory behind these modeling tecniques and critically analyze the results of their analysis.	6	ING-INF/06	48	-	-	-	Attività formative affini ed integrative	ENG
1049268 - SIGNAL PROCESSING AND INFORMATION THEORY	6	ING-INF/03	48	-	-	-	Attività formative affini ed integrative	ENG
1049269 - ALGORITHMS (obiettivi) this course is an introduction to algorithms with special emphasis given to those algorithmic problems and techniques that have the greatest impact for bioinformatics.	6	INF/01	48	-	-	-	Attività formative affini ed integrative	ENG
1049270 - COMPLEX BIOMOLECULAR NETWORKS (obiettivi) The course aims to provide basics concepts and tools for complex networks analysis. The attendee will be able to apply complex networks concepts to biological networks and explore the underlying process and molecular related issues.	6	ING-INF/05	48	-	-	-	Attività formative affini ed integrative	ENG
1049271 - PLANT FUNCTIONAL GENOMICS (obiettivi) The aim of the course is to provide a theoretical knowledge of plant genomes, and practical explanation of the techniques used in plant functional genomics, i.e. a large-scale analysis of the function of the different gene products to understand how the genome generates the phenotype of the plant. Insights will be given into the new information that will be generated from whole genome-/proteome-/metabolome analysis. The course will cover the following concepts: array and sequencing based methods; reverse and forward genetics; comparison of plant genomes; epigenomics; proteomics and metabolomics. Also covered are robotization, miniaturization (single-cell studies) and high-throughput-screenings. Finally, the course will introduce methods for visualization and analysis of high-density data.	6	BIO/04	48	-	-	-	Attività formative affini ed integrative	ENG
1049272 - PRINCIPLES OF GENERAL PATHOLOGY	6	MED/46	48	-	-	-	Attività formative affini ed integrative	ENG
1049273 - OPTIMIZATION METHODS FOR COMPUTATIONAL BIOLOGY (obiettivi) We aim to introduce students to the analysis of decision problems that arise in bioinformatics and health management. Students would be able to: model as mathematical programming problem to be used as a support to the decision maker, use algorithm suitable to each model for the solution, make post-optimality analysis.	6	MAT/09	48	-	-	-	Attività formative affini ed integrative	ENG
1049285 - BIOINFORMATICS IN PLANT PATHOLOGY (obiettivi) Recent advances in -omics technology, namely genomics, proteomics and metabolomics allow to go deeper into the understanding of the subtle mechanism underlying host-pathogen interactions. This is made possible by next generation sequencers that uncover entire genome or exome of host and pathogens while interacting, skipping complicate procedures for separating the two challengers. Moreover, we are moving faster in re-shaping plant pathology from the one disease-one pathogen dogma, as embodied in Koch's postulate, to the pathobiome concept. Meta-omic tools shed light on the inter-reign network originating the disease of the host in its complexity. The analysis and understanding of the huge amount of data generated by a single experiment represents currently the classical bottleneck. In relation to this, bioinformatics plays a crucial role in data capture, analysis and integration. Plant pathologists have to answer to very concrete and problematic question, today, more, and more in the next future: food security, food safety and food quality. Actually, plant disease burden current food production, accounting for more than 40% of food losses. Climate change and globalization enhance pathogens ability and mobility worldwide. Nevertheless, for environmental as well as political reasons, pathogens cannot be controlled anymore by using pesticides and/or GMO plants. A more sustainable, "green" and integrated pest management is needed. A modern plant pathologist has to face this complex reality, plan experiments at real scale, "sucks the marrow out of -omics" (par. Walt Whitman) by using bioinformatics tools, individuate biocontrol agents and stimulate plant self-defences. In relation to this, the main aim of this course is forming young scientists in managing plant diseases tout court by the mean of the -omics plus bioinformatics tools.	6	AGR/12	48	-	-	-	Attività formative affini ed integrative	ENG

Secondo semestre

Insegnamento

CFU

SSD

Ore Lezione

Ore Eserc.

Ore Lab

Ore Studio

Attività

Lingua

Gruppo opzionale: Gruppo OPZIONALE - (visualizza)

1049267 - MODELLING AND SIMULATION OF BIOMOLECULAR DYNAMICAL SYSTEMS (obiettivi) This course aims to provide students with a practical and hands-on experience with common modeling and simulation tools in molecular biology. It would be expected that after completing this course a student would be able to model and simulate using Matlab a biomolecular systems like, for example, a gene regulatory network using the appropriate methodology. Further, students will understand the basic theory behind these modeling tecniques and critically analyze the results of their analysis.	6	ING-INF/06	48	-	-	-	Attività formative affini ed integrative	ENG
1049268 - SIGNAL PROCESSING AND INFORMATION THEORY	6	ING-INF/03	48	-	-	-	Attività formative affini ed integrative	ENG
1049269 - ALGORITHMS (obiettivi) this course is an introduction to algorithms with special emphasis given to those algorithmic problems and techniques that have the greatest impact for bioinformatics.	6	INF/01	48	-	-	-	Attività formative affini ed integrative	ENG
1049270 - COMPLEX BIOMOLECULAR NETWORKS (obiettivi) The course aims to provide basics concepts and tools for complex networks analysis. The attendee will be able to apply complex networks concepts to biological networks and explore the underlying process and molecular related issues.	6	ING-INF/05	48	-	-	-	Attività formative affini ed integrative	ENG
1049271 - PLANT FUNCTIONAL GENOMICS (obiettivi) The aim of the course is to provide a theoretical knowledge of plant genomes, and practical explanation of the techniques used in plant functional genomics, i.e. a large-scale analysis of the function of the different gene products to understand how the genome generates the phenotype of the plant. Insights will be given into the new information that will be generated from whole genome-/proteome-/metabolome analysis. The course will cover the following concepts: array and sequencing based methods; reverse and forward genetics; comparison of plant genomes; epigenomics; proteomics and metabolomics. Also covered are robotization, miniaturization (single-cell studies) and high-throughput-screenings. Finally, the course will introduce methods for visualization and analysis of high-density data.	6	BIO/04	48	-	-	-	Attività formative affini ed integrative	ENG
1049272 - PRINCIPLES OF GENERAL PATHOLOGY	6	MED/46	48	-	-	-	Attività formative affini ed integrative	ENG
1049273 - OPTIMIZATION METHODS FOR COMPUTATIONAL BIOLOGY (obiettivi) We aim to introduce students to the analysis of decision problems that arise in bioinformatics and health management. Students would be able to: model as mathematical programming problem to be used as a support to the decision maker, use algorithm suitable to each model for the solution, make post-optimality analysis.	6	MAT/09	48	-	-	-	Attività formative affini ed integrative	ENG
1049285 - BIOINFORMATICS IN PLANT PATHOLOGY (obiettivi) Recent advances in -omics technology, namely genomics, proteomics and metabolomics allow to go deeper into the understanding of the subtle mechanism underlying host-pathogen interactions. This is made possible by next generation sequencers that uncover entire genome or exome of host and pathogens while interacting, skipping complicate procedures for separating the two challengers. Moreover, we are moving faster in re-shaping plant pathology from the one disease-one pathogen dogma, as embodied in Koch's postulate, to the pathobiome concept. Meta-omic tools shed light on the inter-reign network originating the disease of the host in its complexity. The analysis and understanding of the huge amount of data generated by a single experiment represents currently the classical bottleneck. In relation to this, bioinformatics plays a crucial role in data capture, analysis and integration. Plant pathologists have to answer to very concrete and problematic question, today, more, and more in the next future: food security, food safety and food quality. Actually, plant disease burden current food production, accounting for more than 40% of food losses. Climate change and globalization enhance pathogens ability and mobility worldwide. Nevertheless, for environmental as well as political reasons, pathogens cannot be controlled anymore by using pesticides and/or GMO plants. A more sustainable, "green" and integrated pest management is needed. A modern plant pathologist has to face this complex reality, plan experiments at real scale, "sucks the marrow out of -omics" (par. Walt Whitman) by using bioinformatics tools, individuate biocontrol agents and stimulate plant self-defences. In relation to this, the main aim of this course is forming young scientists in managing plant diseases tout court by the mean of the -omics plus bioinformatics tools.	6	AGR/12	48	-	-	-	Attività formative affini ed integrative	ENG

AAF1749 - FOR THE FINAL TEST (obiettivi)

Per la prova finale e la lingua straniera (art.10, comma 5, lettera c)

ENG

AAF1750 - FURTHER LINGUISTIC KNOWLEDGE

Ulteriori attività formative (art.10, comma 5, lettera d)

ENG

AAF1752 - STAGES AND PROFESSIONAL TRAINING (obiettivi)

Ulteriori attività formative (art.10, comma 5, lettera d)

ENG

AAF1753 - OTHER KNOWLEDGE USEFUL FOR ENTERING INTO THE WORK MARKET (obiettivi)

Ulteriori attività formative (art.10, comma 5, lettera d)

ENG

- - Elective course

Attività formative a scelta dello studente (art.10, comma 5, lettera a)

ENG

TOTALE

180

Corso di laurea: Bioinformatica A.A. 2017/2018

Obiettivi formativi e sbocchi professionali Regolamento didattico del corso Programmazione

Autonomia di giudizio

Abilità comunicative

Capacità di apprendimento

Requisiti di ammissione

Prova finale

Orientamento in ingresso

Il Corso di Studio in breve